Chemistry and Biodiversity 2013-Oct
New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis.
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Two new pterosin sesquiterpenes, (2S)-13-hydroxypterosin A (1) and (2S,3S)-12-hydroxypterosin Q (2), were isolated from the whole plants of Pteris ensiformis, together with six known compounds. The structures of 1 and 2 were determined through extensive 1D/2D-NMR and MS analyses. Compound 2 exhibited antitubercular activity (MIC 6.25 μg/ml) against Mycobacterium tuberculosis H37 Rv in vitro.
