cimigenol/actaea cimicifuga

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Simultaneous determination of cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside in beagle dog plasma by LC-MS/MS.

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A selective and sensitive LC-MS/MS method was developed and validated for the simultaneous determination of five constituents (cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside) of Cimicifuga foetida L. in beagle dog plasma. The

[Cycloartane triterpenoid of Cimicifuga foetida].

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OBJECTIVE To study cycloartane triterpenoid of Cimicifuga foetida and their osteoclast inhibition activity. METHODS The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition

Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida.

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A tetranor-cycloartane glycoside and two 9,19-cycloartane glycosides were isolated from the EtOAc-soluble fraction of the rhizome of Cimicifuga foetida. The structures of the compounds were determined to be cimilactone A (1), 25-O-acetylcimigenol 3-O-beta-d-xylopyranoside (2) and cimigenol

Two new cyclolanostanol glycosides from the aerial parts of Cimicifuga foetida.

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Two new cyclolanostanol glycosides, cimifoetiside IV (1) and cimifoetiside V (2) and two known compounds have been isolated from the aerial part of Cimicifuga foetida L. On the basis of spectral and chemical evidences, the structures of 1 and 2 were elucidated to be

[Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida].

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OBJECTIVE To find new active constituents from the aerial part of Cimicifuga foetida. METHODS Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences. RESULTS Four

[Studies on new trierpenoid constituents from the Rhizoma of Cimicifuga foetida].

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OBJECTIVE To find new active constituents from Rhizome of Cimicifuga foetida. METHODS Various column chromatographic techniques were employed for isolation and purification. The structures were elucidated on the basis of spectral and chemical evidences. RESULTS Four triterpenoid compounds were

[Studies on the triterpenoid constituents from the aerial part of Cimicifuga foetida L].

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OBJECTIVE To look for new active constituents from the aerial part of Cimicifuga foetida L. METHODS Various column chromatographic techniques were used for the isolation and purification of the ingredients. The structure were elucidated on the basis of spectral evidences and chemical

[Studies on the chemical constituents of the aerial part of Cimicifuga foetida L].

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OBJECTIVE To look for new active constituents from the aerial part of Cimicifuga foetida L. METHODS Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical

Cycloartane triterpenoids from the aerial parts of Cimicifuga foetida Linnaeus.

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Cycloartane triterpenoids, 2',24-O-diacetylisodahurinol-3-O-α-L-arabinopyranoside, 24-O-acetylisodahurinol-3-O-α-L-arabinopyranoside, 12β-hydroxy-25-anhydrocimigenol, cimigenol-12-one, 12β-hydroxy-15-deoxycimigenol, 2'-O-acetyl-24-epi-cimigenol-3-O-α-L-arabinopyranoside,

Studies on the constituents of Cimicifuga foetida collected in Guizhou Province and their cytotoxic activities.

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Two new triterpenoids and a chromone glycoside, namely, 24-epi-cimigenol-3-one (1), foetinoside (2), cimifugin-4'-O-[6″-feruloyl]-β-D-glucopyranoside (3), together with 18 known compounds, were isolated from the rhizomes of Cimicifuga foetida L. collected in Guizhou Province, China. All of the

Cimicifoetisides A and B, two cytotoxic cycloartane triterpenoid glycosides from the rhizomes of Cimicifuga foetida, inhibit proliferation of cancer cells.

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Two new cycloartane-type triterpene glycosides, namely cimicifoetisides A (1) and B (2), along with seven known compounds cimigenol, 25-O-acetylcimigenol, cimigenol 3-O-beta-D-xylopyranoside, 12beta-hydroxycimigenol 3-O-beta-D-xylopyranoside, cimigenol 3-O-alpha-L-arabinopyranoside,

Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products.

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Black cohosh has become one of the most important herbal products in the US dietary supplements market. It is manufactured from roots and rhizomes of Cimicifuga racemosa (Ranunculaceae). Botanical identification of the raw starting material is a key step in the quality control of black cohosh

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