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Methoxsalen (MTS) is a natural bioactive compound found in a variety of plants that has many known biofunctions; however, its effects on osteoporosis and related mechanisms are not clear. This study examined whether MTS exhibited preventive effects against postmenopausal osteoporosis. Female C3H/HeN
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Twenty-six patients with long-standing, recurrent polymorphous light eruptions were treated with psoralen photochemotherapy. Thirteen patients received oral methoxsalen, while 13 were photosensitized by trioxsalen baths. After an average of 20 PUVA exposures, a good or excellent therapeutic result
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Topical 8-methoxypsoralen (8-MOP) was used to briefly provide free psoralen sufficient for marked cutaneous photosensitization, but only a small dose of UVA was delivered initially, in an effort to produce many monoadducts but few crosslinks. After ample time for clearance of the remaining free
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Vitiligo is an acute disease of skin with inflammation which means damage of melanocites, their defined partial paint lack. It is a frequent sickness which is very conspicuous and disturbing illness. For its treatment, systematically and topically psoralen-derivatives, UV-A radiation and other
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In human adult volunteers, oral 8-methoxypsoralen and UVA (PUVA) caused an almost linear dose-response effect in depleting adenosine 1--5 J/cm2 were used. A higher dose did not appreciably augment the LC depleting effect although the intensity of the PUVA-induced skin inflammation increased. After a
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Low-fluence carbon dioxide (CO2) laser irradiation of skin has previously been shown to induce damage limited primarily to the epidermis. To evaluate whether this technique was therapeutically effective for pigmented epidermal lesions, ten lentigines caused by methoxsalen and ultraviolet light
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A 45-year-old male with chronic myelocytic leukemia who received a bone marrow transplantation from a phenotypically HLA-matched unrelated donor developed chronic GVHD on day 100 post transplantation. He developed a slight fever, malaise, hepatic dysfunction and extensive itchy erythema with scaling
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Sterile pustules and crusted vegetative plaques on the trunk and limbs developed in a 24-year-old man. They left cribriform scars after healing. Histologically, the lesions showed epidermal proliferation and pustulosis resembling that found in "pyoderma vegetans" and pemphigus vegetans. The lesions
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BACKGROUND
Extracorporeal photochemotherapy (ECP) using UVA irradiation of enriched leukocytes in the presence of methoxsalen as a photoactivatable substrate has been employed for the treatment of several immunologically mediated disorders.
OBJECTIVE
Our purpose was to determine the efficacy and
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The morphological and numerical changes in epidermal melanocytes in tail skin of C57BL mice after exposure to psoralen followed by UVA irradiation were studied. The dorsal aspect of the tail was painted daily for 5 days a week with 0.1 ml methoxsalen (8-methoxypsoralen) in acetone, followed by UVA
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Oral administration of 8-methoxypsoralen followed by exposure to longwave ultraviolet light (primarily ultraviolet A, 320-400 nm) is used in the treatment of vitiligo and psoriasis. 8-Methoxypsoralen also occurs naturally in a variety of vegetables. Toxicology and carcinogenesis studies of
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Several cytochrome P450 enzymes are known to be down regulated by nitric oxide (NO). CYP2A6 is responsible for the metabolism of nicotine and several other xenobiotics, but its susceptibility to down-regulation by NO has not been reported. To address this question, we used HuH7 human hepatoma cell
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Botanical extracts and single compounds are increasingly used in cosmetics but also in over-the-counter drugs and food supplements. The focus of the present review is on controlled clinical trials with botanicals in the treatment of acne, inflammatory skin diseases, skin infections, UV-induced skin
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Photopheresis (extracorporeal photochemotherapy) is an immunomodulatory therapy that entails the reinfusion of peripheral blood mononuclear cells after exposure to the photoreactive agent methoxsalen and ultraviolet A (UVA) radiation. Currently available at approximately 150 treatment centers
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BACKGROUND
Extracorporeal photopheresis (ECP) involves ex vivo leukocyte treatment with methoxsalen and UVA light to generate a tolerogenic response. A previous trial demonstrated that ECP permits corticosteroid withdrawal in steroid-dependent Crohn's disease (CD) patients who were in clinical
Bilim tarafından desteklenen en eksiksiz şifalı otlar veritabanı
55 dilde çalışır
Bilim destekli bitkisel kürler
Görüntüye göre bitki tanıma
Etkileşimli GPS haritası - bölgedeki bitkileri etiketleyin (yakında)
Aramanızla ilgili bilimsel yayınları okuyun
Şifalı bitkileri etkilerine göre arayın
İlgi alanlarınızı düzenleyin ve haber araştırmaları, klinik denemeler ve patentlerle güncel kalın
Bir belirti veya hastalık yazın ve yardımcı olabilecek bitkiler hakkında bilgi edinin, bir bitki yazın ve karşı kullanıldığı hastalıkları ve semptomları görün. * Tüm bilgiler yayınlanmış bilimsel araştırmalara dayanmaktadır