palicourea padifolia/seizures

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The relationships between neuronal activity and behavioral seizures induced by Palicourea marcgravii in rats.

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To characterize the convulsions induced by an aqueous extract of Palicourea marcgravii (Pm), male Wistar rats were injected sc with 3.75 g/kg of the extract, and electroencephalogram and behavior were observed for periods up to 180 min after the Pm injections. Sleep spindles and generalized

Palicourea marcgravii intoxication in rats: effects of different fractions.

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Palicourea marcgravii (Pm) is the most toxic plant in Brazil to cattle. Previous experiments showed that Pm experimental intoxication in rats is similar to that reported for cattle, and these symptoms include generalized itching, incoordination, depression, tonic-clonic seizures and death. The

Effects of acetamide on experimentally-induced Palicourea marcgravii (St Hill) poisoning in rats.

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High indices of mortality in cattle have been reported in Brazil as a consequence of Palicourea marcgravii (Pm) acute intoxications. It has been established that Pm leaves contain monofluoroacetic acid (MFA), the active toxic principle of the plant. Rational therapy for MFA poisoning involves the

Is monofluoracetic acid the active neurotoxic principle in Palicourea marcgravii (St. Hill) leaves?

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Acute intoxication of rats with the crude extract of Palicourea marcgravii (PM) and with monofluoracetic acid (MFA) solutions was compared since it has been reported that PM leaves contain monofluoracetates (455 micrograms/g air-dried material). The neurotoxic signs produced by oral administration

Effect of CNS depressant drugs on acute intoxication from Palicourea marcgravii St Hill in rats.

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Palicourea marcgravii (Pm) is a highly toxic plant to cattle in Brazil. Previous experiments showed that Pm intoxication in rats is similar to that reported for cattle. The present study was undertaken to determine if central nervous system depressant drugs protected animals against Pm-induced

Chemical and biological demonstration of the presence of monofluoroacetate in the leaves of Palicourea marcgravii St. Hil.

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Cattle losses in Brazil have been attributed to Palicourea marcgravii St. Hil., a toxic plant for cattle. The crude extract from the leaves of P. marcgravii was successively fractionated using solvents with different polarities to determine whether monofluoroacetic acid and/or some other substance

Analysis of the toxic potential of Palicourea corymbifera (Müll. Arg.) Standl. in laboratory animals.

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Palicourea species may produce bovine toxicity. Palicourea corymbifera grows in terra firme forests within the Amazon rain forest and in Tropical America, particularly in spots that gave place to gazing areas. The lyophilized extract done with the aerial organs of P. corymbifera were analyzed in

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