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STUDIES ON THE PATHOGENESIS OF FEVER AND TISSUE INJURY IN PNEUMOCOCCAL INFECTION.

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Studies on the pathogenesis of fever. V. The fever accompanying pneumococcal infection in the rabbit.

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Comparison of invasive pneumococcal disease caused by serotype 19A and non-19A pneumococci in children: more empyema in serotype 19A invasive pneumococcal disease.

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OBJECTIVE To delineate whether serotype 19A invasive pneumococcal disease (IPD) comprised significantly more necrotizing pneumonia and empyema in children, we compared the clinical characteristics between serotype 19A and non-19A IPD. METHODS Between January 2007 and December 2011, cases of children

Invasive pneumococcal disease in children prior to implementation of the conjugate vaccine in the Zurich region, Switzerland.

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OBJECTIVE To describe symptoms, disease manifestations and outcome of invasive pneumococcal disease in children prior to implementation of the pneumococcal vaccine. METHODS Analysis of children younger than 16 years of age with invasive pneumococcal disease (IPD; n = 119). Children with

Post-streptococcal acute glomerulonephritis associated with pneumococcal infection.

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Streptococcus pyogenes is the most common cause of post-infectious glomerulonephritis. Described herein is the case of a 5-year-old girl with febrile post-streptococcal acute glomerulonephritis (PSAGN) associated with pneumococcal bacteremia. The chief complaints were fever and macrohematuria

[Invasive pneumococcal disease and consolidated pneumonia in infants: one year of surveillance in three Chilean health care centers].

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OBJECTIVE To describe frequency and type of invasive pneumococcal diseases (IPD) and consolidated pneumonia (CP) in Chilean infants. METHODS One-year prospective surveillance in three health care centers. PID surveillance: blood culture in infants with suspected invasive bacterial disease or with

Systematic review and meta-analysis of the effects of antipyretic medications on mortality in Streptococcus pneumoniae infections.

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OBJECTIVE To determine whether the use of antipyretic medications in the treatment of Streptococcus pneumoniae infection affects mortality in humans or animal models. METHODS A systematic search of Medline, Embase, and The Cochrane Register of Controlled Trials was undertaken to identify in vivo

Evaluation of a rapid urine antigen assay for the detection of invasive pneumococcal disease in children.

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OBJECTIVE Streptococcus pneumoniae remains the most common cause of occult bacteremia, bacterial pneumonia, and meningitis in young febrile children. We sought to determine the utility of a pneumococcal urine antigen assay among young febrile children at varying risk of invasive pneumococcal

Viral coinfections in children with invasive pneumococcal disease.

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BACKGROUND Respiratory viruses contribute to the seasonal pattern of invasive pneumococcal disease (IPD), but the impact of viral coinfections on the clinical characteristics and outcomes of patients with IPD have not been well defined. OBJECTIVE This study was designed to describe and compare the

Vertebral Osteomyelitis Secondary to Pneumococcal Infection.

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Vertebral osteomyelitis secondary to pneumococcal infection is an uncommon condition caused by Streptococcus pneumoniae. Fever, back pain, and raised ESR are common features in the clinical setting. We report a 62-year-old female patient who presented with an unusual presentation. Later on,

Fever without apparent source on clinical examination.

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OBJECTIVE This review discusses recent literature that has focused on the epidemiology, clinical and laboratory evaluation and treatment of episodes of acute illnesses associated with fever and also of prolonged episodes of fever in children. RESULTS Articles addressed the epidemiology of invasive

A study of the relationship between the fever caused by bacterial pyrogens and the fever accompanying acute infections.

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The relationship between the fever of acute infection and that following injection of bacterial pyrogen was studied by administering pyrogens to animals convalescent from acute infections. Rabbits surviving dermal pneumococcal infections or peritonitis due to Escherichia coli were given intravenous

Immunogenicity and safety of a 23-valent pneumococcal polysaccharide vaccine in healthy children and in children at increased risk of pneumococcal infection.

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Splenectomized children as well as those suffering from nephrotic syndrome or recurrent asthmatic bronchitis have an increased susceptibility to systemic pneumococcal infections compared to healthy children. To determine the immunogenicity and safety of a 23-valent pneumococcal polysaccharide

[Serious invasive pneumococcal disease in young children: the importance of vaccination].

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In three children with fever, two girls aged 8 and almost 10 months and one boy aged 5 months, invasive pneumococcal disease was present. The youngest girl presented with pneumococcal sepsis which was complicated by haemolytic uraemic syndrome--she recovered--and the boy developed fulminant fatal

American Academy of Pediatrics. Committee on Infectious Diseases. Technical report: prevention of pneumococcal infections, including the use of pneumococcal conjugate and polysaccharide vaccines and antibiotic prophylaxis.

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Pneumococcal infections are the most common invasive bacterial infections in children in the United States. The incidence of invasive pneumococcal infections peaks in children younger than 2 years, reaching rates of 228/100,000 in children 6 to 12 months old. Children with functional or anatomic

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