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Tricyclic antidepressant plasma levels after fluoxetine addition.

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After a review of a pharmacokinetic interaction between tricyclic antidepressants (TCA) and fluoxetine the authors report their own data. They confirm the existence of an interaction of TCA with fluoxetine, in clinical practice, but the fluoxetine was not associated in all cases with a marked

Elevated antidepressant plasma levels after addition of fluoxetine.

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Four patients treated with tricyclic antidepressants and one patient treated with trazodone all demonstrated marked increases in plasma levels of these drugs after the addition of fluoxetine. Such increases could increase adverse effects.

Carbamazepine addition in tricyclic antidepressant-resistant unipolar depression.

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Rapid antidepressant effect of addition of lithium to tranylcypromine.

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A chronically depressed patient who had not responded to treatment with several tricyclic antidepressants and monoamine oxidase inhibitors alone, responded within hours following the addition of lithium to ongoing tranylcypromine treatment in a double-blind medication trial. The findings are

Manic symptoms following addition of lithium to antidepressant treatment.

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Lithium addition in treatment-resistant depression.

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The addition of lithium to antidepressants as a strategy for the management of depressed patients not responding to a tricyclic antidepressant was derived from the observation in animals that long-term administration of tricyclic antidepressant drugs enhances the sensitivity of postsynaptic

Comparison of 2 treatment strategies for depressed inpatients: imipramine and lithium addition or mirtazapine and lithium addition.

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BACKGROUND The purpose of this study was to compare the overall effectiveness of 2 treatment strategies for inpatients with severe major depressive episode (DSM-III-R): (1) mirtazapine (phase 1) and subsequent lithium addition (phase 2) or (2) imipramine (phase 1) and subsequent lithium addition

Lithium addition to a tricyclic antidepressant results in optimal efficacy.

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Improvement of Neuropsychiatric Lupus with Addition of SSRI Antidepressant/Antipsychotic Therapy.

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Neuropsychiatric lupus erythematosus (NPLE) is a major cause of morbidity and mortality. We report a case involving an adolescent female who developed acute NPLE, manifesting as acute delusional depression with suicidal ideation. Despite high-dose corticosteroid therapy, these symptoms persisted.

The addition of lithium to carbamazepine. Antidepressant efficacy in treatment-resistant depression.

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The addition of lithium carbonate to various antidepressant agents, including heterocyclics and monoamine oxidase inhibitors, has been reported to rapidly effect an antidepressant response in otherwise treatment-unresponsive depressed patients. Fifteen depressed patients diagnosed by DSM-III

Does addition of gabapentin to antidepressant therapy improve control of hot flashes?

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Bright light treatment an effective addition to antidepressants for non-seasonal depression.

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[Addition of lithium to thymoleptic drugs in the treatment of therapy refractory depression].

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The paper gives a short overview of the open and controlled investigations which have been published on the subject. The therapeutic efficacy of lithium addition is now quite well documented, and its use may be recommended in depressions refractory to conventional thymoleptic drug treatment.

Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy.

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Cases of profound hypoglycemia after the initiation of tricyclic antidepressant therapy in two patients taking sulfonylureas are described. To the authors' knowledge, this is the first report of a potential drug interaction between tricyclic antidepressants and sulfonylureas.

Stimulant medication addition to antidepressant in an adolescent with difficult to treat depression.

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