Coconut Oil in Cardiovascular Disease
Ключові слова
Анотація
Опис
The universe of patients with coronary artery disease (CAD) has been increasing steadily worldwide. And associated intimately with certain cardiovascular risk factors such as dyslipidemia , decreased HDL-C , hypertension , diabetes mellitus and obesity. The quality of the fat in the diet influences the incidence of obesity and dyslipidemia. A high intake of saturated fat in different populations is associated with elevated serum cholesterol concentration and cardiovascular mortality. However, studies have shown that extra virgin coconut oil (Cocos nucifera L.) despite being characterized by its high content of saturated fat was not associated with obesity and dyslipidemia in populations that had their high consumption . And this is due to the high proportion of medium chain triglycerides , especially lauric acid in proportions ranging from 45-50 % , and the presence of factors antioxidants like vitamin E and polyphenols. Our hypothesis is that extra virgin coconut oil associated with a nutritional treatment has an effect on weight reduction and control of dyslipidemia contributes to control in secondary prevention in patients with coronary artery disease. All participants will be informed about the research and they must sign a consent form . Volunteers will be divided into two groups : a group receiving dietary treatment for 6 months and the other beyond the dietary treatment during the 6 months starts to receive supplementation with coconut oil extra virgin from 3 months, both groups evaluated monthly . At each visit , weight assessment , compliance with diet and blood pressure measurement is performed. In addition , the blood will also be collected for determination of glucose, insulin, total cholesterol, LDL-cholesterol , HDL-cholesterol, triglycerides , apolipoprotein A and B. The results will be analyzed by the statistical program.It is expected that the results obtained, the extra virgin coconut oil can be used as a coupled secondary prevention in patients with coronary artery disease.Our hypothesis is that extra virgin coconut oil associated with nutritional treatment has an effect on weight reduction and control of dyslipidemia contributes to control in secondary prevention in patients with coronary artery disease.
Дати
| Востаннє перевірено: | 09/30/2013 |
| Перший поданий: | 10/07/2013 |
| Орієнтовна реєстрація подана: | 10/09/2013 |
| Опубліковано вперше: | 10/13/2013 |
| Останнє оновлення надіслано: | 10/09/2013 |
| Останнє оновлення опубліковано: | 10/13/2013 |
| Фактична дата початку навчання: | 12/31/2011 |
| Розрахункова дата первинного завершення: | 02/28/2014 |
| Розрахункова дата завершення дослідження: | 02/28/2014 |
Стан або захворювання
Втручання / лікування
Dietary Supplement: extra virgim coconut oil group
Behavioral: Nutritional treatment
Фаза
Групи рук
| Рука | Втручання / лікування |
|---|---|
| Other: Nutritional treatment All patients received an individualized diet plan and balanced. The diet was calculated according to the nutritional status and the protein 15-20% of total energy value, lipids 25-30% of daily energy intake and carbohydrate 50-60% of of total energy value | Behavioral: Nutritional treatment Patients were instructed to follow the dietary treatment for 6 months |
| Experimental: extra virgim coconut oil group Oil from coconuts (cocos nucifera L.) contains a high proportion of medium chain fatty acids, principally the lauric acid (12:0), in proportions that range from 45 to 50% | Dietary Supplement: extra virgim coconut oil group Patients were followed for 6 months with dietary treatment. Beginning supplementation with coconut oil extra virgin from the third month of intervention nutrition. Coconut oil was consumed neat or added to fruit. |
Критерії прийнятності
| Вік, придатний для навчання | 20 Years До 20 Years |
| Стать, яка підходить для вивчення | All |
| Приймає здорових добровольців | Так |
| Критерії | Inclusion Criteria: Presenting chronic coronary artery disease (myocardial infarction and/or stable angina Exclusion Criteria: angioplasty and/or coronary artery bypass grafting and previous cardiovascular event <6 months and those who had chronic renal failure with creatinine values> the 2mg/dl and liver disease. |
Результат
Заходи первинного результату
1. Anthropometry [3 months]
Заходи вторинного результату
1. Lipid profile [3 months]
2. Quality of the diet [3 months]
