Cases of monochorionic / diamniotic twin pregnancies diagnosed with twin-twin transfusion syndrome.

Controls of monochorionic / diamniotic twin pregnancies without a diagnosis of twin-twin transfusion syndrome.

Twin Twin Transfusion Syndrome

Doppler ultrasound assessment of the proximal fetal renal artery to with measurement of the peak systolic velocity, resistive index, pulsatility index, and systolic/diastolic ratio.

Doppler ultrasound of fetal renal artery

Columbia University Medical Center

Renal Artery Dopplers in Twin Twin Transfusion Syndrome

Are Renal Artery Doppler Indices Different Between Monochorionic Diamniotic Twins With Twin-twin Transfusion Syndrome and Monochorionic Diamniotic Twins Without Twin-twin Transfusion Syndrome?

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the peak systolic velocity for twin A.

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the resistive index for twin A.

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the pulsatility index for twin A.

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the peak systolic velocity for twin B.

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the resistive index for twin B.

Doppler ultrasound assessment of the proximal fetal renal artery with measurement of the pulsatility index for twin B.

There is no plan to share individual participant data with other researchers.

Russell Miller

Assistant Professor of Obstetrics and Gynecology

Columbia University

Patients will be selected from Rh isoimmunized patients (positive titre of indirect coomb's test) who are scheduled to have intrauterine blood transfusion. This intrauterine blood transfusion is due to fetal anemia, and it is detected when the measurement of PSV (peak systolic velocity) of middle cerebral artery is more than 1.5 MoM (multiple of the median) according to Fetal Medicine unit of Cairo University protocol. All fetuses are free of structural and functional Fetal and echocardiographic anomaly scan.

Fetal Anemia as Antepartum Condition (Diagnosis)

Rh Incompatible Blood Transfusion Nos

Venous and arterial Doppler indices:
Middle cerebral artery (MCA) peak systolic velocity (PSV):
Umbilical Artery Pulsitility Index (PI) and Resistant Index (RI):
Ductus venosus (DV) Doppler:
Cardiac functions:
Global cardiac function evaluated by Modified Myocardial Performance Index (Mod-MPI):
Systolic cardiac function using the four-dimensional (4D) spatiotemporal imaging correlation (STIC) ultrasound technique:
Diastolic cardiac function evaluated by relationship between the maximal velocities of the E and A waveforms of ventricular filling (E/A ratio)

Mid trimesteric fetal ultrasonography

Cairo University, Faculty of Medicine, Obstetrics and Gynecology Department, Cairo Fetal Medicine Unit.

Cardiac Functions as a New Method for Evaluation of Fetal Anemia Pre and Post Intrauterine Fetal Blood Transfusion

the ratio between summation of isovolumetric contraction time (ICT) + isovolumetric relaxation time (IRT) in melliseconds and ejection time (ET) in melliseconds

Fetal Hemoglobin (Hb) levels which is measured by g/dl. A blood sample is collected from umbilical vein prior to blood transfusion (Sample 1) and another blood sample (Sample 2) after blood transfusion just before withdrawing of the trnsfusion needle from umbilical vein

MCA PSV will be identified by using pulsed wave Doppler in cm/s

The relationship between the maximal velocities of the E and A waveforms of ventricular filling

National Research Center, Egypt

Cairo University

This will be a prospective study. Patients will be selected from Rh isoimmunized patients (positive titre of indirect coomb's test) who are scheduled to have intrauterine blood transfusion.Selected patients will be monitored weekly from 15 weeks gestational age till 28 weeks of gestational age.

hydrops fetalis/hypoxia

Renal Artery Dopplers in Twin Twin Transfusion Syndrome

Cardiac Functions as a New Method for Evaluation of Fetal Anemia Pre and Post Intrauterine Fetal Blood Transfusion

Найповніша база даних про лікарські трави, підкріплена наукою