Cognitive Change

Mood

Inflammatory Response

Brain Derived Neurotrophic Factor Level

Satiety

Control

50 grams walnuts mixed with 50 gram breakfast cereal.

50 g Walnut

University of Reading

The Acute Effect of a Walnut Intervention on Cognitive Performance , Brain Activation, and Serum Markers of Inflammation in Young Adults

AVLT - Recall of a previously presented list of words following a 25 minute delay.

AVLT - Visual Recognition of a previously presented list of words following a 25 minute delay.

Accuracy performance on the Modified Attention Network Task

Reaction time performance on the Modified Attention Network Task

Accuracy performance on the switching task

Reaction time performance on the switching task

Change in ERP measure of N2 latency and amplitude

Change in ERP measure of P3 latency and amplitude

Change in blood serum markers of inflammation

Satiety Measure recorded on a 100 millimetre scale. Scores closer to 0 millimetres indicate less hunger - taken as a positive outcome, less satiety - taken as a negative outcome, less fullness - taken as a negative outcome, and less desire for prospective food consumption - taken as a positive.

Changes in Power for Alpha, Beta, Gamma, Delta, and Theta bands during performance of each cognitive task.

AVLT - Immediate recall following first presentation of the word list

AVLT - Area under the curve for first five word list recalls.

AVLT - Immediate recall following final presentation of the word list

AVLT - Immediate recall of second (interference) list.

The full dataset will be anonymized and made available on the University of Reading Research Data Archive.

Prof Claire Williams

Chair of Neuroscience

California Walnut Commission

Tufts University

Participants will be assigned to both the walnut and control conditions in a randomised order.

Participants will be aware the possible contents of each treatment, however, neither the participants or investigators will be aware of which treatment the participants are receiving at the point of testing. All analysis will be performed in relation to a treatment code which will only be revealed once analysis is completed.

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The Acute Effect of a Walnut Intervention on Cognitive Performance , Brain Activation, and Serum Markers of Inflammation in Young Adults

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