BO1, propriety blend of cooking oil containing rice bran, flaxseed and sesame oil blended at proportions different from 'Blended Oil 2

BO2, propriety blend of cooking oil containing rice bran, flaxseed and sesame oil blended at proportions different from 'Blended Oil 1

Hyperlipidemias

Consumption of chicken dishes made with ROO for a period of 8 weeks

Refined olive oil (ROO)

Consumption of chicken dishes made with BO1 for a period of 8 weeks

Blended Oil 1 (BO1)

Consumption of chicken dishes made with BO2 for a period of 8 weeks

Blended Oil 2 (BO2)

Clinical Nutrition Research Centre

Blended Oil Beneficial for Blood Lipids Management

Blood will be collected in plain serum tubes after an overnight fast, centrifuged and frozen within 2 hours of collection

Blood will be collected in EDTA tubes after an overnight fast, centrifuged and frozen within 2 hours of collectionBlood will be collected in EDTA tubes after an overnight fast, centrifuged and frozen within 2 hours of collection

measured using DEXA (Dual-Energy X-ray Absorptiometry)

Measured using Omron blood pressure monitor after an overnight fast in a seated posture, at rest. Blood pressure measured for a minimum of 3 times and the average of the final 2 readings were taken, ensuring that they were within 10 mmHg of each other.

Assessed using gut metagenome and metatranscriptome profiling

JeyaKumar Henry

Principal Investigator

Wilmar International Limited

National University, Singapore

Agency for Science, Technology and Research

12 volunteers will receive a single oral dose of CBD in a sesame oil vehicle filled in a capsule, with 200 mL of water. The dose of CBD to be administrated is 90 mg.

12 volunteers will receive a single oral dose of CBD-LNL formulation filled in a capsule, with 200 mL of water. The dose of CBD to be administrated is 90 mg.

12 volunteers will receive a single oral dose of CBD in powder form filled in a hard gelatin capsule, with 200 mL of water. The dose of CBD to be administrated is 90 mg.

Pain

A capsule containing cannabidiol dissolved in sesame oil and surfactant vehicle.

CBD-sesame oil capsule

A capsule containing Cannabidiol dissolved in self nano emulsifying formulation

CBD-LNL capsule

Powder of Cannabidiol filled in a hard gelatin capsule, without formulation.

CBD powder form capsule

Hadassah Medical Organization

Bioequivalence Assessment of Cannabidiol (CBD) Administrated in Oral Formulations

Assesment of the pharmacokinetic profile of Cannabidiol in healthy volunteers. Plasma concentrations will be determined using HPLC-MS/MS validiated assay. The unit of measure will be provided as ng/ml.

Assessment of the metabolic profile of the major cannabidiol metabolites: 7-hydroxy-CBD and CBD-glucoronide-11 in healthy volunteers. Plasma metabolites concentrations will be determined using HPLC-MS/MS validiated assay. The unit of measure will be provided as ng/ml.

randomized blind, three way cross-over study

sesamum angustifolium/triglyceride

Blended Oil Beneficial for Blood Lipids Management

Bioequivalence Assessment of Cannabidiol (CBD) Administrated in Oral Formulations

Найповніша база даних про лікарські трави, підкріплена наукою