Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2011-Jul
[Chemical constituents of Carya cathayensis and their antitumor bioactivity].
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OBJECTIVE
To investigate the chemical constituents of Carya cathayensis and their antitumor bioactivity.
METHODS
The compounds were isolated by Sephadex LH-20 and silica gel column chromatography. Their structures were identified by physicochemical properties and spectroscopic analysis. Then their cytotoxic activity was studied.
RESULTS
Five compounds were elucidated as chrysophanol (1), physcion (2), beta-sitosterol (3), pinostrobin(4), 4,8-dihydroxy-1-tetralone (5).
CONCLUSIONS
Compounds 2 and 5 are isolated from Carya cathayensis for the first time. In the MTT antitumor experiments, the compounds 1,4 and 5 have the cytotoxic activity to KB cell.
