Beijing Vascular Disease Patients Evaluation STudy
关键词
抽象
描述
This study aimed to establish vascular disease early detection system and scoring systems by comprehensive vascular disease risk factors and vascular function evaluation index. And prevention of vascular-related diseases, high-risk groups through positive lifestyle changes: such as lipid-lowering, smoking cessation, reversing early vascular lesions, to avoid end-stage vascular events.
1. Detection of vascular function indicators include: PWV, IMT, CFVR, FMD, CAVI, ABI, LDL-C, HOMA-IR, hs-CRP, Hcy, BNP, UA and so on.
2. Design the questionnaire: surveying the lifestyle, personal history, family history of the study population.
3. Follow-up:2 years of observation, recording the end time of vascular events, including cardiovascular events (acute myocardial infarction, angina, coronary reperfusion therapy), stroke, heart failure, peripheral vascular disease.
4. Statistics: Complex the factors of vascular disease, screen for an effective indicator to predict cardiovascular events, and based on the weight of the different factors, the establish the rating system, use the system to predict the incidence of vascular events terminal, and compare the system with the previous scoring system such as FRS (Framingham Risk Score).
日期
最后验证: | 04/30/2016 |
首次提交: | 09/29/2015 |
提交的预估入学人数: | 10/01/2015 |
首次发布: | 10/05/2015 |
上次提交的更新: | 05/06/2016 |
最近更新发布: | 05/09/2016 |
实际学习开始日期: | 12/31/2011 |
预计主要完成日期: | 11/30/2015 |
预计完成日期: | 11/30/2015 |
状况或疾病
干预/治疗
Other: exposure population
相
手臂组
臂 | 干预/治疗 |
---|---|
exposure population No special intervention(s) . | Other: exposure population Detecting the vascular functional parameters, questionnaire and follow-up: For 2 years or the occurrence of vascular events end time, including cardiovascular events (acute myocardial infarction, angina, coronary reperfusion therapy), stroke, heart failure, peripheral vascular disease. |
资格标准
有资格学习的年龄 | 45 Years 至 45 Years |
有资格学习的性别 | All |
取样方式 | Non-Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: 1. health subjects with or without history of vascular-related diseases; or 2. hypertension subjects; or 3. diabetes mellitus subjects; or 4. coronary artery disease; or 5. cerebrovascular disease;or 6. hyperlipidemia subjects. Exclusion Criteria: 1. severe infectious diseases and inflammatory diseases; 2. liver and kidney failure; 3. cancer; 4. immunological diseases; 5. hematological system diseases。 |
结果
主要结果指标
1. Number of vascular diseases-related death [Up to 1 year]
次要成果指标
1. Number of acute coronary syndrome [Up to 1 year]
2. Number of acute stroke [Up to 1 year]
3. Number of acute heart failure [Up to 1 year]
4. Number of peripheral arteriosclerosis occlusion [Up to 1 year]