Chinese Atherosclerosis Risk Evaluation- Phase II
关键词
抽象
日期
最后验证: | 11/30/2013 |
首次提交: | 12/03/2013 |
提交的预估入学人数: | 12/15/2013 |
首次发布: | 12/22/2013 |
上次提交的更新: | 12/15/2013 |
最近更新发布: | 12/22/2013 |
实际学习开始日期: | 12/31/2011 |
预计主要完成日期: | 05/31/2014 |
预计完成日期: | 11/30/2014 |
状况或疾病
相
资格标准
有资格学习的年龄 | 18 Years 至 18 Years |
有资格学习的性别 | All |
取样方式 | Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - Patients with recent TIA of ischemic stroke (2 weeks) and carotid plaque determined by ultrasound will be included in this study. Exclusion Criteria: - Patients with contraindications to MR scan - Patients with hemorrhagic stroke - Patients with evidence of cardiogenic stroke - Patients with brain tumors - Patients underwent carotid revascularization therapy, such as stenting and endarterectomy |
结果
主要结果指标
1. Prevalence of carotid vulnerable plaques, defined as lesions with intraplaque hemorrhage, fibrous cap rupture, or lipid core occupying >40% of vessel wall area as determined by high resolution, black-blood MR imaging in this study population. [within two weeks after symptom onset]
次要成果指标
1. Carotid wall and brain infarct measurements. [within two weeks after symptom onset]
2. Traditional risk factors. [within two weeks after symptom onset]
3. Incidence and volume of carotid plaques and geographic region of subjects. [within two weeks after symptom onset]