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Digestion of Foods Consumed in Africa

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赞助商
Purdue University
合作者
Baylor College of Medicine

关键词

抽象

As populations become urbanized in Africa, the change to a more Westernized diet has been associated with rise in obesity and related metabolic syndrome diseases. The current study shows that in the West African Sahel, these replacement starchy staple foods have fast gastric emptying compared to traditional sorghum and millet foods; and implies that the latter could be beneficial in lowering glycemic response, providing energy from a meal over a longer time, and providing a satiety effect. Knowledge of this attribute of sorghum and millet foods could be useful to improve their image in West African cities to increase their consumption and to improve markets for local smallholder farmers.

描述

As suggested by anecdotal evidence that traditional Malian sorghum and millet foods are filling and provide sustained energy, we hypothesized that gastric emptying rates of sorghum and millet foods are slow, particularly compared to non-traditional starchy foods (white rice, potato, wheat pasta) that are now commonly consumed in urban areas of the West African Sahel. A broader purpose for the study was to understand whether sorghum and millet foods have positive health attributes that can be promoted in urban areas to provide better markets for local farmers.

Two human trials of similar design were conducted approximately one year apart. The carbon 13 (13C)-labelled octanoic acid breath test method was used to measure gastric emptying rate, and subjective pre-test and satiety response questionnaires were used. In the first study, 14 healthy volunteers in Bamako, Mali participated in a crossover design to test eight starchy foods for gastric emptying rate and satiety feelings. The second study with six volunteers was done to correct for endogenous 13C differences in the starch component of the foods.

日期

最后验证: 11/30/2016
首次提交: 10/31/2016
提交的预估入学人数: 12/28/2016
首次发布: 01/01/2017
上次提交的更新: 12/28/2016
最近更新发布: 01/01/2017
实际学习开始日期: 02/29/2012
预计主要完成日期: 03/31/2013
预计完成日期: 04/30/2013

状况或疾病

Obesity and Other Hyperalimentation

干预/治疗

Other: Rice

Other: Potato

Other: Pasta

Other: Sorghum thick porridge

Other: Millet thick porridge

Other: Millet couscous

Other: Millet thin porridge

Other: Millet thin monikuru porridge

-

手臂组

干预/治疗
Experimental: Rice
Cooked white rice and tomato-based sauce
Other: Rice
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Potato
Cooked white peeled potato and tomato-based sauce
Other: Potato
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response .
Experimental: Pasta
Cooked macaroni product and tomato-based sauce
Other: Pasta
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Sorghum thick porridge
Sorghum thick porridge and tomato-based sauce
Other: Sorghum thick porridge
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Millet thick porridge
Millet thick porridge and tomato-based sauce
Other: Millet thick porridge
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Millet couscous
Cooked millet couscous and tomato-based sauce
Other: Millet couscous
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Millet thin porridge
Millet thin porridge
Other: Millet thin porridge
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.
Experimental: Millet thin monikuru porridge
Millet thin porridge containing cooked millet granules (monikuru)
Other: Millet thin monikuru porridge
Different modern and traditional starch-based foods found in Bamako, Mali were tested for differences in gastric emptying rate and appetitive response.

资格标准

有资格学习的年龄 20 Years 至 20 Years
有资格学习的性别All
接受健康志愿者
标准

Inclusion Criteria:

- Normal body mass index (18 kg/m2 ≤ BMI ≤ 25 kg/m2)

Exclusion Criteria:

- Under any medication

- History of any gastrointestinal disease or surgery

- Diabetes

- Smoker

结果

主要结果指标

1. Gastric emptying [acute study, 4 hours after consumption of test food]

Breath test was performed using 13C-octanoic acid mixed into test meals

次要成果指标

1. Appetitive response [acute study, 4 hours after consumption of test food]

Fullness and hunger questionnaire was given at various time points after consumption of test foods

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