Digestive Properties of Carbohydrate-based Foods
关键词
抽象
描述
Anecdotal evidence suggests that couscous made from pearl millet (Pennisetum glaucum), hereby referred to as millet couscous, is highly satiating in populations living in the West African Sahel. Results from a previous human study conducted the investigators indicated that traditional West African foods made from pearl millet and sorghum (millet couscous, millet thick porridge, and sorghum thick porridge) exhibit markedly delayed rates of gastric emptying compared to Western foods (pasta, boiled potatoes, and white rice) in a population from Mali, Africa. The delayed gastric emptying rate of the thick porridges can be attributed at least partially to the impact of viscosity, while the cause of the delayed gastric emptying rate of the millet couscous remains unclear. The overall aim of this research is to determine why millet couscous exhibits a delayed rate of gastric emptying, while also assessing other digestive properties to gain a better understanding of the factors that could be contributing to this outcome. Therefore, gastric emptying rate, glycemic response, fermentation, and appetitive response are all being assessed for West African and Western foods in a population residing in the United States.
日期
| 最后验证: | 07/31/2019 |
| 首次提交: | 06/26/2018 |
| 提交的预估入学人数: | 08/08/2018 |
| 首次发布: | 08/13/2018 |
| 上次提交的更新: | 08/20/2019 |
| 最近更新发布: | 08/21/2019 |
| 实际学习开始日期: | 06/10/2018 |
| 预计主要完成日期: | 07/30/2018 |
| 预计完成日期: | 07/30/2018 |
状况或疾病
干预/治疗
Other: Pearl millet couscous - made in Senegal
Other: Pearl millet couscous - made in USA
Other: Pearl millet thick porridge
Other: Wheat couscous
Other: White rice
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: Pearl millet couscous - made in Senegal Steamed pearl millet couscous - commercially produced in Senegal | Other: Pearl millet couscous - made in Senegal Pearl millet couscous (made in Senegal) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response. |
| Experimental: Pearl millet couscous - made in USA Steamed pearl millet couscous - pearl millet obtained from Senegal but processed and prepared in USA | Other: Pearl millet couscous - made in USA Pearl millet couscous (made in USA) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response. |
| Experimental: Pearl millet thick porridge Thick porridge prepared according to traditional West African methods with pearl millet obtained from Senegal but processed and prepared in USA | Other: Pearl millet thick porridge Pearl millet thick porridge was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response. |
| Experimental: Wheat couscous Steamed wheat couscous - wheat flour processed and prepared in USA | Other: Wheat couscous Wheat couscous was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response. |
| Active Comparator: White rice White rice - medium-grain prepared using a rice cooker | Other: White rice White rice was tested as a comparator for gastric emptying rate, glycemic response, fermentability, and appetitive response. |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Normal body mass index (18.5 < BMI < 25 kg/m2) - Normal fasting blood glucose Exclusion Criteria: - Diabetes - Allergy to millet - Allergy or sensitivity/intolerance to gluten - History of gastrointestinal disease - Pregnant or nursing |
结果
主要结果指标
1. Gastric emptying rate [Acute study; 4 hours of measurement after consumption of test food]
2. Glycemic response [Acute study; 4 hours of measurement after consumption of test food]
次要成果指标
1. Breath hydrogen (fermentability) [Acute study; 4 hours of measurement after consumption of test food]
2. Appetitive response [Acute study; 4 hours of measurement after consumption of test food]
