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Effect of Ginseng on Glycemic Control

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St. Michael's Hospital, Toronto

关键词

抽象

Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis model assessment of insulin resistance [HOMA-IR]).

描述

Ginseng has demonstrated to have significant hypoglycemic effect. Its major pharmacological component is considered to be ginsenosides. Several trials have been undertaken in diabetes some of which have demonstrated advantages in glycemic control in both diabetic as well as non diabetic individuals although clinical consistency of results is lacking.The lack of high quality data in this area to support diabetes recommendations represents an urgent call for stronger evidence. A systematic review and meta-analysis of controlled trials remains the "Gold Standard" of evidence for recommendations and clinical guidelines development. Therefore, investigators will conduct a systematic review and meta-analyses of controlled trials to assess the effect of ginseng on glycemic control.

日期

最后验证: 04/30/2013
首次提交: 04/22/2013
提交的预估入学人数: 04/24/2013
首次发布: 04/25/2013
上次提交的更新: 05/21/2013
最近更新发布: 05/22/2013
实际学习开始日期: 09/30/2012
预计主要完成日期: 04/30/2013
预计完成日期: 04/30/2013

状况或疾病

Impaired Glucose Tolerance
Diabetes

-

资格标准

有资格学习的性别All
取样方式Probability Sample
接受健康志愿者
标准

Inclusion Criteria:

- Dietary trials in humans

- Randomized treatment allocation

- 1 month

- Suitable control

- Viable endpoint data

Exclusion Criteria:

- Non-human studies

- Non-randomized treatment allocation

- <1 month

- Lack of a suitable control

- No viable endpoint data

结果

主要结果指标

1. Glycated hemoglobin (HbA1c) [1month]

次要成果指标

1. Fasting blood glucose [1month]

2. Fasting plasma insulin [1 month]

3. Homeostasis model assessment of insulin resistance (HOMA-IR) [1 month]

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