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Effects of Almond Versus Pistachio on Weight Loss

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赞助商
Novindiet Clinic
合作者
University of Nottingham
Tehran University of Medical Sciences

关键词

抽象

The purpose of the current study is comparing the effect of almond and pistachio, as the two common types of nuts, consumption on healthy obese and overweight female who following a hypocaloric diet for 12 weeks. The secondary aim of the current study is to evaluate of these two type of nuts on other cardiometabolic risk factors.

日期

最后验证: 02/28/2018
首次提交: 04/14/2017
提交的预估入学人数: 04/14/2017
首次发布: 04/18/2017
上次提交的更新: 03/27/2018
最近更新发布: 03/28/2018
实际学习开始日期: 06/04/2017
预计主要完成日期: 11/12/2017
预计完成日期: 01/14/2018

状况或疾病

Obesity
Overweight

干预/治疗

Behavioral: Almond group (AG)

Behavioral: Pistachio group (PG)

Behavioral: Nut Free (NFG, CG)

-

手臂组

干预/治疗
Experimental: Almond group (AG)
Obese or overweight female adults will be randomly allocated to have have almond as afternoon snack while they have a hypoenergetic diet.
Behavioral: Almond group (AG)
Obese or overweight female adults will be randomly allocated to have almond as afternoon snacks, while they have a hypoenergetic diet.
Active Comparator: Pistachio group (PG)
Obese or overweight female adults will be randomly allocated to have have Pistachio as afternoon snack while they have a hypoenergetic diet.
Behavioral: Pistachio group (PG)
Obese or overweight female adults will be randomly allocated to have Pistachio as afternoon snacks, while they have a hypoenergetic diet.
Placebo Comparator: Nut Free (NFG, CG)
Obese or overweight female adults are asked to avoid all nuts, seeds, and nut products while they have a hypoenergetic diet. , as the control group.
Behavioral: Nut Free (NFG, CG)
Obese or overweight female adults will be asked to avoid nuts, seeds and nut products, while they have a hypoenergetic diet.

资格标准

有资格学习的年龄 18 Years 至 18 Years
有资格学习的性别Female
接受健康志愿者
标准

Inclusion Criteria:

- Must be female

- Must be 18-45 years of age.

- Must have Body mass index (BMI) between 27-35 kg/ m².

- Must be able to have moderate exercise.

- Must be interested to have weight loss.

Exclusion Criteria:

- Have allergy to nuts

- Participating in a research project involving weight loss or physical activity in the previous six months.

- Pregnancy or lactation during the previous 6 months, or planned pregnancy in the next six months.

- Taking medication that could affect metabolism or change body weight.

- Report heart problems, chest pain, and cancer within the last five years.

- Smoking

- Menopause

- Diagnosis of any chronic disease such as fatty liver, cancer, chemo/radio therapy, heart disease, immune compromised conditions, abnormal thyroid hormone level.

结果

主要结果指标

1. Weight [12 Weeks]

Body weight was taken to the nearest 0.1 kg using a digital calibrated scale (Omron Health Care, Hoofddorp, Netherland), whilst subjects wore light clothing and no shoes.

次要成果指标

1. Waist circumference [12 Weeks]

Waist circumference (WC) was measured with a rigid measuring tape and recorded to the nearest 0.5 cm. WC was measured at the smallest horizontal circumference between the ribs and iliac crest (the natural waist), or, in case of an indeterminable waist narrowing, halfway between the lower rib and the iliac crest.

2. fasting blood glucose [12 Weeks]

Fasting plasma glucose (FPG) were measured using the enzymatic colorimetric method.

3. HbA1c [12 Weeks]

Glycated hamoglobin (HbA1c) was measured by a colorimetric method after an initial separation by ion exchange chromatography (Biosystem, Barcelona, Spain).

4. HOMA-IR [12 Weeks]

Insulin resistance was evaluated by homeostasis model assessment of insulin resistance (HOMA-IR), which was calculated by using the following formula HOMA-IR = [fasting insulin (mU/l) × FPG (mmol/l)]/22.5

5. lipid profiles [12 Weeks]

Biochemical analysis of the serum total cholesterol (TC), triglyceride (TG), and high-density lipoprotein (HDL) cholesterol was carried out on a Selectra E auto analyzer (Vita Laboratory, Netherlands) following standard procedures of the Pars Azmoon diagnostic kits (Iran). The LDL cholesterol was calculated using the Friedewald formula. LDL cholesterol = TC - HDL cholesterol + (TG ÷ 2.2)

6. liver function tests [12 Weeks]

AST ALT

7. Insulin [12 Weeks]

Insulin was measured by using a radioimmunoassay with 125I-labeled human insulin and a human insulin antiserum in an immunoradiometric assay (IRMA) (Biosource, Dorest, Belgium) with a gamma-counter system (Gamma I; Genesys).

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