Effects of Isoflavone Combined With Astaxanthin on Skin Aging
关键词
抽象
日期
| 最后验证: | 05/31/2016 |
| 首次提交: | 02/19/2015 |
| 提交的预估入学人数: | 02/24/2015 |
| 首次发布: | 02/25/2015 |
| 上次提交的更新: | 06/10/2016 |
| 最近更新发布: | 06/13/2016 |
| 实际学习开始日期: | 02/28/2015 |
| 预计主要完成日期: | 10/31/2015 |
| 预计完成日期: | 11/30/2015 |
状况或疾病
干预/治疗
Dietary Supplement: Isoflavone and Astaxanthin
Dietary Supplement: Isoflavone and Astaxanthin
Dietary Supplement: Placebo
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Active Comparator: Isoflavone and Astaxanthin Each subject takes one active tablet per day for 24 weeks. Each tablet contains isoflavone 27mg and astaxanthin 4mg. | Dietary Supplement: Isoflavone and Astaxanthin |
| Placebo Comparator: Placebo Each subject takes one placebo tablet per day for 24 weeks. | Dietary Supplement: Placebo |
资格标准
| 有资格学习的年龄 | 45 Years 至 45 Years |
| 有资格学习的性别 | Female |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Healthy females aged ≥ 45 years - Facial wrinkle grade 2 to 4 Exclusion Criteria: - received medical or cosmetic treatment that interferes with the general aging process at least 3 months before the study - received any hormone replacement therapy at least 3 months before the study - reported taking functional foods more than 1 month during last 3 months before the study - history of acute or chronic disease such as severe liver or kidney disease - history of allergies against any component of trial foods - any visible skin disease that might be confused with a skin reaction to the test procedure |
结果
主要结果指标
1. Change from baseline in skin wrinkles [Twenty-four weeks]
次要成果指标
1. Change from baseline in skin elasticity [Twenty-four weeks]
2. Change from baseline in epidermal hydration [Twenty-four weeks]
3. Change from baseline in skin barrier integrity [Tewnty-four weeks]
