Exercise Intervention Metabolic Syndrome Prostate Cancer Black Men
关键词
抽象
描述
The specific aim for the proposed study is to examine the feasibility and impact of a 6-month two-arm randomized controlled trial (RCT) on MetS components and biomarkers related to prostate cancer in Black men with MetS. Due to the striking racial disparities of prostate cancer, this proposal will focus on the impact of an aerobic and resistance exercise intervention on MetS and biomarkers related to prostate cancer in Black men. Specifically, our proposed clinical trial compares an aerobic and resistance exercise intervention to an attention control group among Black men.
日期
| 最后验证: | 08/31/2014 |
| 首次提交: | 09/22/2014 |
| 提交的预估入学人数: | 03/03/2015 |
| 首次发布: | 03/04/2015 |
| 上次提交的更新: | 02/16/2017 |
| 最近更新发布: | 02/22/2017 |
| 实际学习开始日期: | 06/30/2013 |
| 预计主要完成日期: | 02/15/2017 |
| 预计完成日期: | 02/15/2017 |
状况或疾病
干预/治疗
Behavioral: Exercise Group
Behavioral: Attention Control Group
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: Exercise Group Eligible participants randomized into the intervention group will receive a mix of supervised moderate-intensity aerobic and light weight-resistance exercises. | Behavioral: Exercise Group For the first 12-weeks, participants will come to our community based research office for up to 50 min/session, 3-days/week of supervised exercise. Exercise duration will increase from 75 min/wk at week 1 to 150 min/wk by week 4. Thereafter, men will maintain 150 min/wk of moderate-intensity physical activity. |
| Active Comparator: Attention Control Group Eligible participants randomized in the attention control group will be asked to maintain their current daily activities and exercise habits for 6-months. | Behavioral: Attention Control Group We will provide weekly healthy lifestyle tips via text messages, and will include tips such as managing stressors in life and getting better sleep. |
资格标准
| 有资格学习的年龄 | 40 Years 至 40 Years |
| 有资格学习的性别 | Male |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: 1. African-American and/or Black men; 2. between the ages of 40-70 years; 3. waist circumference >40 inches (102 cm); 4. with at least two of the following: elevated BP (≥ 130/85 mmHg); 5. elevated fasting glucose (≥ 100 mg/dL), reduced HDL cholesterol (<50 mg/dL), or elevated triglycerides (≥ 150 mg/dL); 6. sedentary defined as <60 minutes of recreation or work requiring modest PA/week; 7. be able to speak and read English; 8. able to provide meaningful consent (i.e., men with severe cognitive impairment will be excluded); 9. have no physical limitations that prevent from exercising; 10. and have access to a television and DVD player. Exclusion Criteria: 1. history of cancer except nonmelanoma skin cancer; 2. current enrollment in another clinical trial or weight loss program; 3. inability to commit to the intervention schedule. Prior to randomization, participants will be required to have a signed authorization and medical clearance from their personal physician or our nurse practitioner. |
结果
主要结果指标
1. Waist circumference [6-months]
次要成果指标
1. Dietary behaviors questionnaire [6-months]
2. Cardiovascular fitness test [6-months]
3. Fasting glucose levels test [6-months]
4. Lipid level test [6-months]
5. Quality of life questionnaire (SF-36) [6-months]
6. Body Mass Index (BMI) [6-months]
