Fast-track Giant Ventral Hernia Repair
关键词
抽象
描述
All patients operated on for a large incisional hernia are treated according to the study protocol. Patients are given high-dose glucocorticoid preoperative and the aim is to discharge patients at postoperative day 3.
Morbidity, length of stay, pain, nausea and pulmonary function are among registered outcomes compared with a historic control group.
日期
| 最后验证: | 08/31/2015 |
| 首次提交: | 11/10/2014 |
| 提交的预估入学人数: | 11/26/2014 |
| 首次发布: | 12/01/2014 |
| 上次提交的更新: | 09/02/2015 |
| 最近更新发布: | 09/06/2015 |
| 实际学习开始日期: | 11/30/2014 |
| 预计主要完成日期: | 06/30/2015 |
| 预计完成日期: | 06/30/2015 |
状况或疾病
干预/治疗
Other: Fast-track group
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Fast-track group Patients treated according to the enhanced recovery pathway. This group is examined prospectively. | Other: Fast-track group Enhanced recovery after surgery pathway. Postoperatively, a set of well-defined discharge criteria will be assessed daily at 9:00 and 15:00, as well as pain, nausea, time to flatus, saturation and drain production. |
| Control group Patients treated according to the historic recovery pathway. This group is examined retrospectively. |
资格标准
| 有资格学习的性别 | All |
| 取样方式 | Non-Probability Sample |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Horizontal fascia defect > 10 cm on computed tomography scan - Planned elective open incisional hernia repair Exclusion Criteria: - Known allergy against glucocorticoid treatment - Insulin-treated diabetes - Gastric ulcer diagnosed within four weeks preoperative - Steroid-treated immune disease - Planned intestinal anastomosis concomitant to hernia repair |
结果
主要结果指标
1. Time to discharge [Participants will be followed for the duration of hospital stay, an expected average of 72 hours]
次要成果指标
1. Fatigue [Preoperative and for the duration of hospital stay, an expected average of 3 days]
2. Pain from supine to standing [Preoperative and for the duration of hospital stay, an expected average of 3 days]
3. Pain when walking 6 meters [Preoperative and for the duration of hospital stay, an expected average of 3 days]
4. Nausea [Preoperative and for the duration of hospital stay, an expected average of 3 days]
5. Time to bowel function [For the duration of postoperative hospital stay, an expected average of 72 hours]
6. Vomiting episodes [Participants will be followed for the duration of hospital stay, an expected average of 3 days]
7. Continuous transcutaneous saturation [From surgery to postoperative day 3 at 12 pm]
8. C-reactive protein from venous blood sample [Preoperative and for the duration of hospital stay, an expected average of 3 days]
9. Ear temperature [Preoperative and for the duration of hospital stay, an expected average of 3 days]
10. Detailed reason for not being discharged if criteria are otherwise fulfilled [From surgery and for the duration of hospital stay, an expected average of 3 days]
11. Daily wound drain production [From surgery and for the duration of hospital stay, an expected average of 3 days]
