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Hematotoxicity in Acute Lymphoblastic Leukemia Children in Maintenance Phase Therapy

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Indonesia University

关键词

抽象

This study use an observational study design from patient medical records to obtain data on patient demographics, nutritional status, 6MP dosing, and albumin levels of LLA child patients.

描述

All medical record data of LLA child patient at maintenance phase therapy, who came to Cipto Mangunkusumo Kiara Hospital in period 2014 - 2016. the data that are colected consist of age, gender, disease stratification, nutritional status, the dosage of 6-MP, albumin levels, hemoglobin levels, leukocyite counts, platelet counts, and absolute neutrophil counts.

日期

最后验证: 08/31/2018
首次提交: 08/27/2017
提交的预估入学人数: 09/10/2017
首次发布: 09/11/2017
上次提交的更新: 09/16/2018
最近更新发布: 09/18/2018
实际学习开始日期: 10/01/2017
预计主要完成日期: 05/15/2018
预计完成日期: 07/15/2018

状况或疾病

Acute Leukemia

-

资格标准

有资格学习的年龄 1 Year 至 1 Year
有资格学习的性别All
取样方式Non-Probability Sample
接受健康志愿者
标准

Medical record of Acute Limphoblastic Leukemia patients at Cipto Mangunkusumo Hospital, in period of 2012 - 2014, with Inclusion Criteria:

- LLA Patients, male and female, age 1 - <18 years

- Received chemotherapy maintenance phase based on Indonesian protocol of ALL - 2013

Exclusion Criteria:

- Incomplete medical record data.

结果

主要结果指标

1. The Incidence of hematotoxicity in acute limphoblastic leukemia children during maintenance phase therapy. [october 2017]

based on medical record data: Incidence of anemia, Neutropenia, and thrombocytopenia in acute limphoblastic leukemia children during maintenance phase therapy.

次要成果指标

1. The relationship of the incidence of hematotoxicity with influencing factors [November 2017]

The relationship of the incidence of hematotoxicity (anemia, Neutropenia, thrombocitopenia) with ALL stratification (High risk or Standard risk, as written in the medical record), nutritional status (normal or malnutrition), and albumin levels (normal or Hypoalbuminemia). The determination of nutritional status is based on body weight (Kg) and Height (Meters). Determination of nutritional status using cutoff Z score based on The growth chart of WHO 2006 for children 0-5 years, and ideal weight percentage according to Waterlow criteria for children above 5 years (recommendation of Indonesian Pediatric Association).

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