STUDY: Effects of Potatoes in a Weight Loss Program
关键词
抽象
描述
The study will examine the effect of including potatoes as part of a calorie restricted diet designed to induce weight loss and improve glycemic control in overweight subjects.
This is a randomized, treatment-controlled, 3-arm, parallel study. The 3 arms of the study will include dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Two diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss and the control diet will be prescribed for weight maintenance. The two energy-restricted diets will include further manipulation, such that, one dietary plan will be a high glycemic index (GI) diet and the other a low glycemic index diet.
日期
| 最后验证: | 04/30/2015 |
| 首次提交: | 08/18/2010 |
| 提交的预估入学人数: | 08/18/2010 |
| 首次发布: | 08/22/2010 |
| 上次提交的更新: | 05/13/2015 |
| 最近更新发布: | 05/17/2015 |
| 实际学习开始日期: | 04/30/2007 |
| 预计主要完成日期: | 10/31/2010 |
| 预计完成日期: | 02/28/2014 |
状况或疾病
干预/治疗
Behavioral: Control
Behavioral: Low Glycemic Index
Behavioral: High Glycemic Index
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: Control Arm includes dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Control diet will be prescribed for weight maintenance. | Behavioral: Control Dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). The control diet will be prescribed for weight maintenance. |
| Experimental: Low Glycemic Index Diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods. | Behavioral: Low Glycemic Index Diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods. |
| Experimental: High Glycemic Index Diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on High Glycemic Index foods. | Behavioral: High Glycemic Index Diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods. |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Men and women - ≥ 18 years of age who have a body mass index (BMI) of 25 to 35 kg/m2 (inclusive). Exclusion Criteria: - Total cholesterol (TC) not greater than 300 mg/dL, - Fasting triglyceride not greater than 300 mg/dL , - LDL cholesterol (LDL-C) not greater than 180 mg/dL, - Smokers - Female subjects who are pregnant or lactating - Subjects taking any medications that would interfere with outcomes of the study - Subjects with unusual dietary habits (eg., pica) - Subjects who are actively losing weight or trying to lose weight - Subjects who are addicted to drugs or alcohol or who are < 1 y in recovery program - Subjects who present with significant psychiatric or neurological disturbances - Subjects with known allergy or intolerance to potato products - Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, uncontrolled hypertension ( 140/90 mm Hg), chronic lung, renal or liver disease |
结果
主要结果指标
1. Weight Loss [12 Weeks]
次要成果指标
1. Glucose tolerance [12 Weeks]
2. Body composition [12 weeks]
3. Blood Pressure [12 weeks]
