Study on Use of Xylitol-wipes to Prevent Dental Caries
关键词
抽象
日期
最后验证: | 10/31/2011 |
首次提交: | 11/06/2011 |
提交的预估入学人数: | 11/07/2011 |
首次发布: | 11/08/2011 |
上次提交的更新: | 11/13/2011 |
最近更新发布: | 11/15/2011 |
实际学习开始日期: | 12/31/2006 |
预计主要完成日期: | 12/31/2007 |
预计完成日期: | 12/31/2007 |
状况或疾病
干预/治疗
Dietary Supplement: xylitol wipe
Dietary Supplement: placebo wipe
相
手臂组
臂 | 干预/治疗 |
---|---|
Experimental: xylitol wipe | Dietary Supplement: xylitol wipe Parents were instructed to wipe their infants' teeth and gums three times per day with two wipes each time after feeding in addition to their daily tooth brushing. |
Placebo Comparator: placebo wipe | Dietary Supplement: placebo wipe Parents were instructed to wipe their infants' teeth and gums three times per day with two wipes each time after feeding in addition to their daily tooth brushing. |
资格标准
有资格学习的年龄 | 6 Months 至 6 Months |
有资格学习的性别 | All |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: 1. mothers presenting with active dental decay or restorations within the past year (high caries risk) 2. mothers who are the primary caregivers for their child 3. healthy children without systemic disease aged 6 months to two years 4. Infants younger than 6 months who have one or more teeth present Exclusion Criteria: 1. mother or child with systemic disease 2. antibiotics or medications taken within the previous 3 months that may alter oral flora and saliva flow for mother or child 3. children who primarily receive care in a daycare center or by a caregiver other than the mother |
结果
主要结果指标
1. new decayed surfaces [1 year]
次要成果指标
1. salivary levels of Mutans Streptococci [3 month, 6 month, 1 year]
2. levels of lactobacilli [3 month, 6 month, and one year]