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Study on the Antiaging Effect of Chinese Herb Drink

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Chung Shan Medical University

关键词

抽象

The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

描述

Background: Si-Wu-Tang (SWT) is a well-known traditional Chinese medicine (TCM) and widely used for treating various gynecological disorders. The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

Methods: Sixty healthy voluntary subjects were recruited and assigned into two groups, who drank 125 mL of placebo (n=30) or SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between. During the initial, 3rd, 6th, 10th, and 13th months anthropometric measurements were performed as well as fasting blood samples were drawn for various biochemical assays. Abdominal ultrasonic and skin examination were performed at the initial, 6th and 13th months.

日期

最后验证: 11/30/2015
首次提交: 12/07/2015
提交的预估入学人数: 12/14/2015
首次发布: 12/17/2015
上次提交的更新: 12/14/2015
最近更新发布: 12/17/2015
实际学习开始日期: 03/31/2008
预计主要完成日期: 03/31/2009
预计完成日期: 03/31/2009

状况或疾病

Gynecological Disorders

干预/治疗

Other: Si-Wu-Tang (SWT)

Other: placebo

-

手臂组

干预/治疗
Experimental: Si-Wu-Tang (SWT)
Subjects are recommended to drink 125 mL of SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between.
Placebo Comparator: placebo
Subjects are recommended to drink 125 mL of Placebo (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between.

资格标准

有资格学习的年龄 20 Years 至 20 Years
有资格学习的性别All
接受健康志愿者
标准

Inclusion Criteria:

- healthy adults

Exclusion Criteria:

- exclusion criteria were history of smoking, alcoholism

- pregnant or lactating women,

- chronic diseases, hepatic or renal dysfunction.

结果

主要结果指标

1. Total thiobarbituric acid reactive substances (TBARS) [6 months]

次要成果指标

1. Glutathione content (GSH) [6 months]

2. Total antioxidant capacity (TEAC)activities. [6 months]

3. Superoxide dismutase (SOD) activity [6 months]

4. GPx and glutathione reductase (GR) activity [6 months]

5. Catalase [6 months]

6. Glutamic oxaloacetic transaminase (GOT) [6 months]

7. Glutamic pyruvic transaminase (GPT) [6 months]

其他成果措施

1. Skin sebum content [6 months]

2. Skin hydration [6 months]

3. Skin surface water loss [6 months]

4. Skin melanin index [6 months]

5. Skin elasticity [6 months]

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