Tart Cherry, Metabolic Syndrome, and Cardiovascular Risk
关键词
抽象
日期
最后验证: | 11/30/2016 |
首次提交: | 05/29/2014 |
提交的预估入学人数: | 05/29/2014 |
首次发布: | 06/02/2014 |
上次提交的更新: | 12/05/2016 |
最近更新发布: | 12/07/2016 |
实际学习开始日期: | 03/31/2014 |
预计主要完成日期: | 09/30/2016 |
预计完成日期: | 09/30/2016 |
状况或疾病
干预/治疗
Dietary Supplement: Tart Cherry
Dietary Supplement: Placebo
相
手臂组
臂 | 干预/治疗 |
---|---|
Experimental: Tart Cherry 12 weeks of tart cherry juice taken in two doses of 240 ml per day. | Dietary Supplement: Tart Cherry 12 weeks of tart cherry juice taken in two doses of 240 ml per day. |
Placebo Comparator: Placebo 12 weeks tart cherry juice taken in two doses of 240 ml per day. | Dietary Supplement: Placebo 12 weeks of tart cherry juice taken in two doses of 240 ml per day. |
资格标准
有资格学习的年龄 | 20 Years 至 20 Years |
有资格学习的性别 | All |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - Three of the following five features at the screening visit: - Waist circumference of ≥ 40 inches for men and 35 inches for women - Serum triglycerides ≥ 150 mg/dL - Serum high density lipoprotein cholesterol levels < 40 mg/dL for men and <50 mg/dL for women - Blood pressure ≥ 130/85 mm Hg - Fasting blood glucose level ≥ 110 mg/dL Exclusion Criteria: - Taking hypoglycemic, antihypertensive or cholesterol-lowering medications - Diagnosed cardiovascular disease - Uncontrolled hypertension (≥ 160/100 mmHg) - Diabetes mellitus - Other active chronic diseases such as cancer, asthma, glaucoma, thyroid, kidney, liver and pancreatic disease - Participating in a weight loss program - Heavy smokers (> 20 cigarettes per day) - Heavy drinkers (> 12 alcoholic drinks per week) - Abnormal menstrual cycle |
结果
主要结果指标
1. Blood Pressure [12 weeks]
2. Arterial Stiffness [12 weeks]
次要成果指标
1. Autonomic Control of Blood Pressure [12 weeks]
2. Endothelial Function [12 weeks]
3. Endothelial-mediated Vasodilation [12 weeks]
4. Inflammation [12 weeks]
5. Oxidative Stress [12 weeks]
6. Insulin Sensitivity [12 weeks]
7. Atherogenic Markers [12 weeks]
8. Body Composition [12 weeks]