The Effect of Berry Extract on Helicobacter Pylori Eradication
关键词
抽象
描述
One-week of triple therapy composed of a proton pump inhibitor plus two antibiotics is currently regarded as the gold standard for HP eradication. However, the eradication rate continues to be disappointing. Poor patient compliance and bacterial resistance are the main factors contributing to treatment failure. Therefore, it is urgently necessary to develop a non-antibiotic alternative therapy to increase the eradication rates of Helicobacter pylori. Some literatures reported that cranberry may inhibit Helicobacter pylori adhesion to the human gastric mucus and may reduce Helicobacter pylori infection in adults. The aims of his experiment were to explore the impact of berry extract on triple therapy for Helicobacter pylori eradication.
日期
| 最后验证: | 12/31/2009 |
| 首次提交: | 12/28/2009 |
| 提交的预估入学人数: | 01/07/2010 |
| 首次发布: | 01/10/2010 |
| 上次提交的更新: | 01/12/2010 |
| 最近更新发布: | 01/13/2010 |
| 实际学习开始日期: | 12/31/2008 |
| 预计主要完成日期: | 11/30/2009 |
| 预计完成日期: | 05/31/2010 |
状况或疾病
干预/治疗
Dietary Supplement: Berry extract
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Placebo Comparator: Berry | |
| Placebo Comparator: Placebo |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Patients older than 18 Exclusion Criteria: - Pregnancy or breastfeeding - Use of antibiotics 2 weeks prior to inclusion - Previous eradication treatment |
结果
主要结果指标
1. Eradication rate [4 weeks after Eradication of Helicobacter pylori]
