Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients
关键词
抽象
描述
Keratosis in feet or plantar callosity is an injury caused by friction or pressure in certain location of the skin. This is a common problem faced by diabetic patients, which usually cause subcutaneous tissue maceration, which favors bacterial invasion. It is responsible for the development of abscesses and ulcers. Ulcer is the main cause of non-traumatic amputation of the feet in diabetic patients. Treatment with medicinal plants is an ancient practice. Brazil has one of the richest floras in the world. Brazilian Ministry of Health recommends the rational use of medicinal plants and encourage the use of this practice by health professionals.
The medicinal plant used in this study is a keratolytic agent, healing, emollient, bactericide and fungicide. The purpose of this study is evaluate the effectiveness of this medicinal plant in the treatment of keratosis in diabetic patients. This study will be controlled, randomized, comparative with standard drug and double-blind. Will be included in the study 90 adult diabetic patients type 1 or 2, with keratosis, both sexes, but do not show feet ulcerated lesions. Patients will be randomised controlled trials in three groups, with 30 people in each, which will receive topical treatment with medicinal plant (treatment group, TG), salicylate 10% (salicylate group, SG) and vaseline cream (control group, CG). The treatment will be once a day, for 30 consecutive days. Numerical scores will be made of the sites with keratosis and individual areas and global measures in the first, 30th days of treatment. The results obtained will be submitted to statistical comparison. This research will follow the standards set by resolution 466/12 of the National Health Council, the Vale do Sapucaí University, for research with human beings and will be conducted in accordance with the ethical recommendations of the Declaration of Helsinki.
日期
最后验证: | 02/28/2019 |
首次提交: | 02/19/2018 |
提交的预估入学人数: | 02/19/2018 |
首次发布: | 02/26/2018 |
上次提交的更新: | 03/04/2019 |
最近更新发布: | 03/05/2019 |
实际学习开始日期: | 05/31/2017 |
预计主要完成日期: | 09/30/2019 |
预计完成日期: | 12/31/2019 |
状况或疾病
干预/治疗
Drug: Medicinal Plant
Drug: Medicinal Plant X Salicylate
Drug: Medicinal Plant X Vaseline
相
手臂组
臂 | 干预/治疗 |
---|---|
Experimental: Medicinal Plant X Salicylate Treatment Group (TG) will receive topical treatment with medicinal plant and Salicylate Group (SG) will receive topical treatment with salicylate 10%, both once a day, for 30 consecutive days. | Drug: Medicinal Plant X Salicylate Salicylate 10% with vaseline cream |
Experimental: Medicinal Plant X Vaseline Treatment Group (TG) will receive topical treatment with medicinal plant and Control Group (CG) will receive topical treatment with vaseline cream, both once a day, for 30 consecutive days. | Drug: Medicinal Plant X Vaseline Vaseline cream |
资格标准
有资格学习的年龄 | 18 Years 至 18 Years |
有资格学习的性别 | All |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - diabetic patients type 1 and 2 with plantar keratosis Exclusion Criteria: - feet ulcerated lesions |
结果
主要结果指标
1. Measures of the sites with plantar keratosis [30 days]