Understanding Loss of Muscle Mass and Function
关键词
抽象
日期
最后验证: | 07/31/2019 |
首次提交: | 06/06/2019 |
提交的预估入学人数: | 06/27/2019 |
首次发布: | 06/30/2019 |
上次提交的更新: | 08/07/2019 |
最近更新发布: | 08/11/2019 |
实际学习开始日期: | 09/30/2018 |
预计主要完成日期: | 07/31/2019 |
预计完成日期: | 07/31/2019 |
状况或疾病
相
资格标准
有资格学习的年龄 | 18 Years 至 18 Years |
有资格学习的性别 | All |
取样方式 | Non-Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - Patients undergoing quadriceps muscle biopsy as part of the treatment. - Patient having given their agreement of conservation within the framework of the care of the biological sample (biopsy and blood sample) Exclusion Criteria: - Subject refusing the detection of anti-HIV, anti-hepatitis C antibodies, HBS antigen - Subject treated with anticoagulant, beta blocker, lipid-lowering agent (statin or fibrate), anti-inflammatory, ACE inhibitors, angiotensin 2 receptor antagonist or corticosteroids, including locally. - Allergic subject to local anesthetics - History or presence of psychoactive substance abuse - History of recent abdominal surgery (less than 3 months) - Subject deprived of liberty by judicial or administrative decision - Major subject protected by law - Inability to understand the nature and purpose of the study and / or communication difficulties with the investigator |
结果
主要结果指标
1. Properties and characterization of satellite cells of healthy subjects compared to satellite cells of subjects with sarcopenia. [6 years]
次要成果指标
1. Reversal of sarcopenia with chemicals compounds extracted from wild aromatic plants from south of France vs control (not treated cells) [5 years]