中文(简体)
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)

Autologous Fat Grafting to the Breast

只有注册用户可以翻译文章
登陆注册
链接已保存到剪贴板
状态
赞助商
Louisiana State University Health Sciences Center in New Orleans

关键词

抽象

Structural fat grafting is a form of tissue transfer where the autologous fat is harvested and subsequently transferred to a different region of the body at the same setting. It is an excellent technique for filling soft tissue and contour defects. Fat has the benefit of being abundantly available and easy to harvest. Further more, it is cheap and autogenous and thus lacks the side effects of synthetic fillers or implants. Autogenous fat transfer is a relatively common procedure performed by plastic and reconstructive surgeons. The goal of fat grafting is to provide the patient with a predictable, long lasting autogenous soft tissue augmentation. Autogenous fat transfer has been used extensively as an adjunct to facial rejuvenation. As well it has been applied to body contouring and augmentation of the hips, trochanteric areas, thighs and buttocks, back, torso and breast. The transfer of autologous fat dates back to 1890s and more specifically as injectable grafts since the 1920s. However, over the past 20 years the popularity of structural fat grafting has increased as a contouring modality. Fat transfer to the breast, popularized by Coleman, has been performed internationally since the 1990s. Despite the duration, the literature lacks accurate outcomes data on fat transfer to the breast and questions regarding the viability of adipocytes after the transfer exist. Sources from various publications show cell viability of up to 100% however studies of long term clinical outcomes quote rates of 10% to 80%.

描述

Our goal with this study is to prospectively acquire information with our protocol that will outline the accurate long-term outcomes of fat transfer to the breast. Currently, fat grafting to the breast is a treatment option in conditions such as micromastia, breast ptosis, post mastectomy breast reconstruction, asymmetric breasts, congenital malformations of breast development and for treatment of complications associated with implant augmentation mammoplasty. In addition to fat grafting, the current surgical treatment for these conditions is mainly based on techniques requiring implant augmentation or reconstruction. Although the safety of saline implants has been well studied and documented, this data cannot be extrapolated for the newer generation silicone implants and other alternatives such as fat grafting need to be investigated. Also implant augmentation and reconstruction comes at the price of capsular contracture, implant deflation, infection and more future corrective surgeries. We plan to prospectively study the outcomes of fat grafting in patients with these conditions for a period of 5 years. The collected information will be entered into a database and will be prospectively collected and reviewed. Patients demographics, information obtained during the preoperative and postoperative visits along with the pertinent findings regarding the fat transfer to the breast will be collected into the database for our investigation.

日期

最后验证: 09/30/2008
首次提交: 10/14/2008
提交的预估入学人数: 10/16/2008
首次发布: 10/19/2008
上次提交的更新: 11/16/2008
最近更新发布: 11/17/2008
实际学习开始日期: 05/31/2008
预计主要完成日期: 05/31/2010
预计完成日期: 05/31/2010

状况或疾病

Micromastia
Breast Ptosis
Implant Failure
Breast Reconstruction
Congenital Malformations

干预/治疗

Procedure: Autologous Fat Grafting to Breasts

-

手臂组

干预/治疗
Experimental: Implant Failure
Experimental: Post mastectomy breast reconstruction
Experimental: Congenital malformations
Experimental: Breast Ptosis
Experimental: Micromastia
Experimental: Asymmetric Breasts

资格标准

有资格学习的年龄 17 Years 至 17 Years
有资格学习的性别Female
接受健康志愿者
标准

Inclusion Criteria:

- Women with the following conditions micromastia, breast ptosis, post mastectomy breast reconstruction, asymmetric breasts, congenital malformations of breast development and for treatment of complications associated with implant augmentation mammoplasty.

Exclusion Criteria:

- A volunteer who has a positive pregnancy test

- A volunteer who has had a cardiac stent placed within the last two months

- A volunteer with a known, current substance abuse

- A volunteer with a bleeding diathesis

- Untreated breast cancer

- A volunteer who smokes cigarettes

- Medical Conditions including untreated hypertension, renal disease, diabetes mellitus

结果

主要结果指标

1. 3 Dimensional volumetric analysis of results and photographic analysis by board certified plastic surgeons. [3 months, 6 months and annually]

次要成果指标

1. Patient satisfaction with cosmetic and reconstructive results [3 months, 6 months and annually]

加入我们的脸书专页

科学支持的最完整的草药数据库

  • 支持55种语言
  • 科学支持的草药疗法
  • 通过图像识别草药
  • 交互式GPS地图-在位置标记草药(即将推出)
  • 阅读与您的搜索相关的科学出版物
  • 通过药效搜索药草
  • 组织您的兴趣并及时了解新闻研究,临床试验和专利

输入症状或疾病,并阅读可能有用的草药,输入草药并查看所使用的疾病和症状。
*所有信息均基于已发表的科学研究

Google Play badgeApp Store badge