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B181: Stimulation of Thermogenesis by Bio-Active Food Ingredients

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赞助商
University of Copenhagen
合作者
Science, Toxicology & Technology, San Francisco, California

关键词

抽象

The primary aim was to measure the effect of green tea extract, tyrosine and caffeine on energy expenditure, appetite ratings and spontaneous energy intake together with recording of side effects in healthy normal weight subjects.

描述

Background: Long-term weight maintenance of a weight loss is often unsuccessful. Often a weight regain is observed in most studies that could indicate that most subjects are not able to change their eating habits. There is a need for simple and safe methods to prevent weight gain and re-gain i.e. by increasing thermogenesis and decrease spontaneous energy intake (EI). Studies have shown that nutritional and food-related non-nutritional factors influence the adjustment of EI and EE as the compounds can enhance the diet-induced thermogenesis (DIT) and suppress appetite.

Method: The present study was designed as a 4-way crossover, randomised, placebo controlled, dou-ble-blind study. Each treatment was separated by >3 d washout period. All treatments were administered as tablets containing either 500 mg green tea extract (whereof 125 mg cate-chins), 400 mg tyrosine, 50 mg anhydrous caffeine, or placebo.

on each test day body weight and composition was assessed. All participants underwent a 4.5-h assessment of energy expenditure by indirect calorimetry in a ventilated hood. Energy intake recorded of an ad libitum pasta salad brunch served after the last hood measurement

Subjects: Twelve healthy lean (20

日期

最后验证: 11/30/2000
首次提交: 03/12/2006
提交的预估入学人数: 03/12/2006
首次发布: 03/13/2006
上次提交的更新: 03/12/2006
最近更新发布: 03/13/2006
实际学习开始日期: 12/31/1999
预计完成日期: 11/30/2000

状况或疾病

Obesity

干预/治疗

Drug: tyrosine, green tea, caffeine

相 1

资格标准

有资格学习的年龄 18 Years 至 18 Years
有资格学习的性别Male
接受健康志愿者
标准

Inclusion Criteria:

- Twelve healthy and normal-weight men (age: 23.72.6 y, BMI: 22.41.8 kg/m2) participated in the study. They were weight stable (within 3-kg in last 3 mo), non-smoking, non-athletic, and had no use of dietary supplements or frequent use of medication.

Exclusion Criteria:

-

结果

主要结果指标

1. heart rate [undefined]

2. blood pressure [undefined]

3. enegy expenditure [undefined]

4. energy intake [undefined]

5. subjective appetite sensations [undefined]

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