Chronic Pain and Minor Breast Cancer Surgery
关键词
抽象
描述
This is a prospective observational study assessing the interest of preoperative thoracic block (injection of local anesthetic around the serratus muscle under ultrasound guidance) in the prevalence of chronic pain 3 months after a conservative breast cancer surgery.
Information on the present survey was given during pre-operative consultation and signed informed consent was obtained to enter the study.
The management of patients undergoing minor surgery for breast cancer is standardized within our department and reported in our previous study. After starting the induction of anesthesia and insertion of a laryngeal mask, a regional analgesia technique was performed under ultrasonography. Twenty ml of ropivacaine 3.75mg/ml were injected under the serratus muscle, at the lateral edge of the minor pectoralis muscle. In the absence of contraindications, multimodal analgesia consisted of paracetamol, non-steroidal anti-inflammatory drugs and nefopam. Postoperative intravenous morphine titration was possible in patients presenting a pain score >3/10 (numeric pain intensity scale from 0 = no pain to 10 = maximum imaginable pain) in the recovery room. If 0.1mg/kg of morphine did not permit to alleviate pain, ketamine titration was initiated by the anesthesiologist.
The incidence of patients that required opioids titration in the recovery room (and the dose injected) was recorded.
The questionnaire sent to the patients 3 months after their surgery was mainly composed of closed questions. This questionnaire included pain score, location of pain, analgesic drugs consumption, neuropathic component (self-administered questionnaire derived from the Neuropathic Pain 4 Questions - DN4 questionnaire), impact of quality of life using the Brief Pain Inventory.
日期
最后验证: | 03/31/2019 |
首次提交: | 04/09/2019 |
提交的预估入学人数: | 04/09/2019 |
首次发布: | 04/10/2019 |
上次提交的更新: | 03/01/2020 |
最近更新发布: | 03/03/2020 |
实际学习开始日期: | 03/31/2019 |
预计主要完成日期: | 09/29/2019 |
预计完成日期: | 12/30/2019 |
状况或疾病
相
资格标准
有资格学习的年龄 | 18 Years 至 18 Years |
有资格学习的性别 | Female |
取样方式 | Non-Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - women - > 18 years old - with "American Society of Anesthesiologists-ASA" physical status 1 to 3 - with unilateral breast cancer adenocarcinoma treated surgically by conservative tumorectomy associated or not to sentinel lymph node dissection on an ambulatory basis Exclusion Criteria: - None |
结果
主要结果指标
1. Prevalence of chronic pain [3 months]
次要成果指标
1. Incidence of pain [3 months]