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Clinical Outcome of Aortic Dissection

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Nanjing Medical University

关键词

抽象

Aortic dissection refers to the blood in the aortic lumen entering the aortic mediastinum from the tear of the aortic intima, separating the mediastinum and extending along the long axis of the aorta to form the true and false separation state of the aortic wall. This disease is rare, and the incidence rate is 100 thousand to 200 thousand a year, with the peak age of 50-70 years old. 65%-70% patients died in the acute stage due to cardiac congestion and arrhythmia, so early diagnosis and treatment is very necessary. The aim of this study is analyze clinical outcome of Chinese patients with acute aortic dissection.

描述

Aortic dissection refers to the blood in the aortic lumen entering the aortic mediastinum from the tear of the aortic intima, separating the mediastinum and extending along the long axis of the aorta to form the true and false separation state of the aortic wall. Risk factors for aortic dissection included hypertension, cystic necrosis or degeneration of the middle aorta, hereditary connective tissue disease, congenital two-lobe active pulse valve, arteritis, aneurysm, atherosclerosis and iatrogenic injury, etc. The leading cause of aortic dissection is hypertension, and more than 75% of aortic dissection is associated with hypertension.Therefore, for hypertension patients to do a good job in the prevention and control of hypertension, pay attention to the regular use of antihypertensive drugs and monitoring blood pressure. In case of sudden chest and back lacerations, the patient should be immobilized in bed, contacted with an ambulance and sent to the hospital for emergency treatment, so as to avoid greater risks. The aim of this study is analyze clinical outcome of Chinese patients with acute aortic dissection.

日期

最后验证: 04/30/2020
首次提交: 05/18/2020
提交的预估入学人数: 05/18/2020
首次发布: 05/21/2020
上次提交的更新: 05/18/2020
最近更新发布: 05/21/2020
实际学习开始日期: 05/31/2020
预计主要完成日期: 12/30/2025
预计完成日期: 12/30/2025

状况或疾病

Aortic Dissection

干预/治疗

Other: observation

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资格标准

有资格学习的年龄 18 Years 至 18 Years
有资格学习的性别All
取样方式Non-Probability Sample
接受健康志愿者
标准

Inclusion Criteria:

- Clinical diagnosis of acute aortic dissection

- Type A dissection

- Type B dissection

- Retrograde type B dissection

Exclusion Criteria:

- Aortic aneurysm

- Myocardial infarction

- Cerebral accident

- Active infection

- Unwillingness to cooperation with study procedures or follow-up visits

结果

主要结果指标

1. Operative mortality [30 days after treatment]

Operative mortality was defined as any death, regardless of cause, occurring whether within 30 days after surgery in or out of the hospital or after 30 days during the same hospitalization subsequent to the operation.

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