Cognitive Behavioural Therapy in Dissociative Seizures
关键词
抽象
描述
Preliminary results from a pilot study demonstrated that cognitive behavioural therapy (CBT) is associated with a significant benefit for patients with dissociative seizures. The current study aims to extend these findings by conducting a randomised controlled trial comparing CBT with standard outpatient medical care. Standard outpatient care has been chosen as the comparison treatment as it most closely resembles what is currently offered to this group of patients by the National Health Service. The primary outcome measure will be seizure frequency. Secondary outcome measures will be work and social adjustment and health service use.
Our hypothesis is that CBT will be superior to standard outpatient care for patients with dissociative seizures as determined by the above measures.
日期
| 最后验证: | 12/31/2008 |
| 首次提交: | 05/29/2008 |
| 提交的预估入学人数: | 06/01/2008 |
| 首次发布: | 06/02/2008 |
| 上次提交的更新: | 01/20/2009 |
| 最近更新发布: | 01/21/2009 |
| 实际学习开始日期: | 02/28/2001 |
| 预计主要完成日期: | 01/31/2009 |
| 预计完成日期: | 01/31/2009 |
状况或疾病
干预/治疗
Behavioral: 1
Behavioral: 2
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: 1 Cognitive behavioural Therapy | Behavioral: 1 CBT, up to 12 sessions. |
| Active Comparator: 2 Standard Care | Behavioral: 2 Routine review by neuropsychiatrist in outpatient clinic |
资格标准
| 有资格学习的年龄 | 16 Years 至 16 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - clinical diagnosis of dissociative seizures - diagnosis confirmed by video EEG telemetry where practicable - aged 16 - 70 Exclusion Criteria: - co existent diagnosis (past or present) of epilepsy - seizure frequency of less than 2 seizures per month - current alcohol or drug abuse - benzodiazepine use exceeding the equivalent of 10mg diazepam per day. |
结果
主要结果指标
1. seizure frequency [previous month]
次要成果指标
1. seizure freedom [3 months]
2. Work & Social Adjustment scale (Marks, 1986) [Pre-treatment, end of treatment and six-months follow-up]
3. Employment Status [Pre-treatment, end of treatment and six-months follow-up]
4. Health Service Use [Pre-treatment, end of treatment and six-months follow-up]
5. Hospital Anxiety and Depression Scale (Zigmond & Snaith, 1983) [Pre-treatment, end of treatment and six-months follow-up]
