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Cranberry Juice for Preventing Bacteria in Urine During Pregnancy

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National Center for Complementary and Integrative Health (NCCIH)

关键词

抽象

The purpose of this study is to determine the amount of cranberry juice that is most effective in preventing a condition in pregnant women that often leads to urinary tract infections (UTIs).

描述

Asymptomatic bacteriuria (ASB) infection, a condition in which a large number of bacteria are present in the urine, often precedes the development of symptomatic UTIs. UTIs are common among women and may create complications during pregnancy. By incorporating cranberry juice into their diets, pregnant women may be able to lower their risk for UTIs caused by ASB, and cranberry juice may also prevent preterm labor and birth. This study will determine the cranberry juice-containing regimen that will work best for preventing ASB in pregnant women.

For the duration of their pregnancy, participants in this study will be randomly assigned to one of three treatment arms: cranberry juice once a day, cranberry juice three times a day, or a placebo beverage three times a day. The level of bacteria in their urine will be measured at monthly study visits. Women who test positive for a UTI will receive oral antibiotic therapy. All women will be monitored throughout their pregnancies for UTIs and other related complications.

日期

最后验证: 12/31/2009
首次提交: 10/06/2004
提交的预估入学人数: 10/06/2004
首次发布: 10/07/2004
上次提交的更新: 01/11/2010
最近更新发布: 01/13/2010
实际学习开始日期: 11/30/2004

状况或疾病

Urinary Tract Infection
Bacteriuria

干预/治疗

Drug: Cranberry juice

相 1

资格标准

有资格学习的年龄 18 Years 至 18 Years
有资格学习的性别Female
接受健康志愿者
标准

Inclusion Criteria:

- Intrauterine pregnancy

- Mother and fetus in good health

- Mother pregnant for 16 weeks or less

Exclusion Criteria:

- Suspected nonviable or ectopic pregnancy

- Mother plans to terminate pregnancy

- Antimicrobial therapy, for reasons other than urinary tract infections, within 2 weeks prior to study start

- Significant underlying medical complications that may interfere with the study

结果

主要结果指标

1. Number of cases of asymptomatic bacteriuria [undefined]

次要成果指标

1. Number of cases of symptomatic urinary tract infection [undefined]

2. Compliance with recommended therapy [undefined]

3. Number of preterm deliveries [undefined]

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