Dietary Intakes and Periodontal Health: A Follow-Up Study
关键词
抽象
描述
Periodontitis is a chronic oral infection that results in the breakdown of connective tissue and alveolar bone that support the teeth. Bacteria and the body's own immune system mediate the severity of periodontitis, where teeth may become loose, fall out or have to be removed. Sanative therapy is a non-surgical process involving mechanical debridement of bacterial biofilms on roots of teeth, below the gum line. Participants in this present study previously underwent sanative therapy several years ago and have been attending the clinic for regular maintenance appointments to maintain periodontal health. While significant associations were observed with higher intakes of fruits and vegetables and specific nutrients (vitamins C and E, beta-carotene, fish oils) within a few months after sanative therapy, this study will follow-up these findings to determine if such relationships persist during a period of relatively stable periodontal health. Given new insights into a potential role of flavonoids in maintaining periodontal health, this aspect will also be studied. The overall objective is to determine if higher intakes of foods, nutrients and supplements known to have osteogenic and immunomodulatory effects are associated with improved clinical outcomes in individuals who previously underwent sanative therapy. At the regular maintenance appointment, clinical measures will be evaluated (clinical attachment loss, probing depth, bleeding on probing, plaque index). As well, the following will be evaluated: dietary intakes of macronutrients and micronutrients using the Block 2015 food frequency questionnaire; intakes of fruit, vegetables and fiber using the Block Dietary Fruit-Vegetable-Fiber Screener; nutritional supplement use and tea intake using specially developed questionnaires and salivary markers of inflammation using biochemical assays.
日期
最后验证: | 04/30/2018 |
首次提交: | 03/02/2017 |
提交的预估入学人数: | 03/02/2017 |
首次发布: | 03/07/2017 |
上次提交的更新: | 05/08/2018 |
最近更新发布: | 05/10/2018 |
实际学习开始日期: | 12/31/2016 |
预计主要完成日期: | 03/31/2018 |
预计完成日期: | 04/30/2018 |
状况或疾病
相
资格标准
有资格学习的年龄 | 19 Years 至 19 Years |
有资格学习的性别 | All |
取样方式 | Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - previously participated in the original study (NCT02291835) Exclusion Criteria: - under 19 years of age - have not participated in the previous study as this study is a direct follow-up of those participants |
结果
主要结果指标
1. Clinical Attachment Loss (CAL) (also called Periodontal Attachment Loss) [At maintenance appointment (1 hour)]
次要成果指标
1. Probing Depth [At maintenance appointment (1 hour)]
2. Bleeding on Probing [At maintenance appointment (1 hour)]
3. Plaque Index [At maintenance appointment (1 hour)]
其他成果措施
1. Dietary Nutrient Intakes [At maintenance appointment (1 hour)]
2. Tea Intakes [At maintenance appointment (1 hour)]
3. Servings of Fruits, Vegetables and Fiber [At maintenance appointment (1 hour)]
4. Dietary Supplement Intakes [At maintenance appointment (1 hour)]
5. Salivary Markers of Inflammation [At maintenance appointment (1 hour)]