Dose Effect of a Plant Extract on Fatigue
关键词
抽象
日期
| 最后验证: | 12/31/2019 |
| 首次提交: | 02/25/2019 |
| 提交的预估入学人数: | 03/07/2019 |
| 首次发布: | 03/10/2019 |
| 上次提交的更新: | 01/13/2020 |
| 最近更新发布: | 01/17/2020 |
| 实际学习开始日期: | 01/28/2019 |
| 预计主要完成日期: | 12/05/2019 |
| 预计完成日期: | 12/05/2019 |
状况或疾病
干预/治疗
Other: Flavored beverage
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Placebo Comparator: Flavored Beverage Mix 1 Flavored still beverage | |
| Experimental: Flavored Beverage Mix 2 Flavored still beverage with polyphenols, concentration 1 | |
| Experimental: Flavored Beverage Mix 3 Flavored still beverage with polyphenols, concentration 2 | |
| Experimental: Flavored Beverage Mix 4 Flavored still beverage with caffeine |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - 18-49 years of age - Self-report of good health - Physical activity requirement: Recreationally active (exercise ≥3 times per week for >30 minutes per session; both cyclists and non-cyclists may enroll) Exclusion Criteria: - Under the care of a physician - Visual impairment that cannot be corrected with glasses or contact lenses - Inability to perform high intensity exercise (defined perceptually as exercise that feels at least "hard" and this is usually quantified using the Borg 6 to 20 scale. High intensity cycling exercise is defined objectively as exercise causing a high heart rate, defined as a heart rate that is equal to or greater than 70% of heart rate reserve.) - Inability to adequately perform the cognitive tasks (i.e., cannot complete the task due to -inability to understand instructions or >50% incorrect responses) - Presence of current or chronic gastrointestinal, sleep or psychiatric disorder - Pregnant/lactating - Current smoker - Report illegal drug use - Report hypersensitivity to caffeine - Food allergies/intolerances/sensitivities (including coffee or related foods/beverages/products) - Current use of dietary supplements, or prescription medication except for oral contraceptives - Unwillingness to abstain from over the counter medications (e.g. NSAIDS, allergy medications) and caffeine/coffee/foods high in polyphenols for 12 hours prior to the study - Unwilling to refrain from consuming apple and grapefruit products on study days and 12 hours prior to test days. - Participation in another clinical trial within the past 30 days or participation in another PepsiCo trial in the past 6 months |
结果
主要结果指标
1. Subjective mental energy: Cognitive test battery [Baseline and 60 min post treatment]
2. Subjective mental energy: VAS for mental alertness [Baseline and 60 min post treatment]
3. Subjective mental energy: VAS for motivation [Baseline and 60 min post treatment]
4. Subjective mental energy: VAS for mental fatigue [Baseline and 60 min post treatment]
5. Subjective mental and physical energy: VAS for mental and physical state and trait energy and fatigue (EFS State Scales) [Baseline and 60 min post treatment]
6. Subjective mental energy: VAS for mood [Baseline and 60 min post treatment]
7. Subjective mental energy: VAS for caffeine symptoms [Baseline and 60 min post treatment]
次要成果指标
1. Physical performance [During the last 3 minutes of 23 min high intensity cycling exercise (10 x 1 min work intervals each followed by 1 min rest. No rest after final interval, 3 min max power from minutes 20-23.]
2. Physical Fatigue [After each of 10 1-minute high intensity cycling intervals separated by 1 min rest and at end of exercise.]
3. Alertness [After each of 10 1-minute high intensity cycling intervals separated by 1 min rest and at end of exercise.]
4. Effort [After each of 10 1-minute high intensity cycling intervals separated by 1 min rest and at end of exercise.]
5. Quadriceps muscle pain [After each of 10 1-minute high intensity cycling intervals separated by 1 min rest and at end of exercise.]
