Exercise Training in Obesity-prone Black and White Women
关键词
抽象
描述
Overweight premenopausal Black and White women are randomized to either diet-only, diet+aerobic or diet+resistance exercise training. Diet/behavior intervention, with or without the aerobic or resistance exercise training, will be provided throughout the 18 months of study. Major outcomes will include measures of perceived and physiologic difficulty of exercise (cardiac, ventilatory, electromyographic responses to standardized exercise tasks); aerobic fitness; strength fitness; and spontaneous free-living energy expenditure (all derived from doubly labeled water). The results will provide insight into the effectiveness of, and the mechanisms by which, different types of exercise training can improve physical fitness, spontaneous engagement in physical activities of daily living and, in turn, weight-loss maintenance.
Time of initial weight loss was defined as the time needed to reach the goal of 25 kg/m2 BMI. The women will then be evaluated one year after this time and the amount of weight gain will be determined.
日期
| 最后验证: | 09/30/2017 |
| 首次提交: | 08/28/2003 |
| 提交的预估入学人数: | 08/28/2003 |
| 首次发布: | 08/31/2003 |
| 上次提交的更新: | 11/15/2017 |
| 最近更新发布: | 11/19/2017 |
| 实际学习开始日期: | 11/30/2000 |
| 预计主要完成日期: | 11/30/2007 |
| 预计完成日期: | 11/30/2007 |
状况或疾病
干预/治疗
Behavioral: Diet
Behavioral: Diet plus aerobic exercise
Behavioral: Diet plus resistance exercise
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Active Comparator: Diet only | |
| Experimental: Diet plus aerobic exercise | Behavioral: Diet plus aerobic exercise |
| Experimental: Diet plus resistance exercise | Behavioral: Diet plus resistance exercise |
资格标准
| 有资格学习的年龄 | 21 Years 至 21 Years |
| 有资格学习的性别 | Female |
| 接受健康志愿者 | 是 |
| 标准 | - Normoglycemic - BMI between 27-30 - Non smoker - Premenopausal - Physically untrained - Family history of obesity |
结果
主要结果指标
1. Weight loss [6 months]
2. Change in weight after initial weight loss [12 months after initial weight loss (maximum 18 months after randomization)]
次要成果指标
1. Insulin sensitivity [6 months post baseline]
2. Insulin sensitivity [18 months post baseline]
3. Change in visceral fat [6 months post baseline]
4. Change in visceral fat [18 months post baseline]
5. Change in cholesterol [6 months post baseline]
6. Change in cholesterol [18 months post baseline]
7. Change in triglycerides [6 months post baseline]
8. Change in triglycerides [18 months post baseline]
9. Change in resting energy expenditure [6 months post baseline]
10. Change in resting energy expenditure [18 months post baseline]
