Impact of Nutritional Intervention in Indian Female Cancer Cachexia Patients
关键词
抽象
描述
Patients were randomly distributed into two groups i.e. control and intervention group. 30 patients were allocated in intervention group and received nutrient rich bread mix i.e. IAtta (100 g) along with dietary and physical activity counseling and 33 patients were allocated in the control group who received only dietary and physical activity counseling. Patients in the intervention group collected 14 packets of 100 g of IAtta every fortnight during their clinician appointments while the control patients were advised regarding their dietary habits at every clinician visit for 6 months.
Dietary counseling for 30 minutes was imparted to all patients on each visit by the researcher. Depending on the physical status of the patients, low level of physical activity (walking and/or stairs), was encouraged daily during counseling sessions.
Nutritional, biochemical, quality of life and anthropometric estimations were assessed at baseline, after 3 months and at 6 months of intervention for all patients.
Patients' daily energy, carbohydrate, protein and fat intake were calculated using food frequency (Indian Migrant study food frequency questionnaire- IMS-FFQ) questionnaire and two day 24 hour recall data. PG-SGA questionnaire was used to monitor patient nutritional status throughout the study.
EORTC-QLQ- C30 questionnaire was used to analyse patients' quality of life and asked personally by the researcher.
Haemoglobin and serum albumin levels were assessed at the start of the study, after 3 months and at 6 months of intervention for all patients.
Indian Migrant Study Physical Activity questionnaire (IMS-PAQ) was used to assess patients' physical activity throughout the day.
Anthropometric estimations included body weight, mid upper arm circumference and four site skin fold thickness (SFT) measurement (i.e. triceps, biceps, subscapular and suprailiac).
日期
| 最后验证: | 12/31/2014 |
| 首次提交: | 01/25/2015 |
| 提交的预估入学人数: | 01/28/2015 |
| 首次发布: | 01/29/2015 |
| 上次提交的更新: | 01/28/2015 |
| 最近更新发布: | 01/29/2015 |
| 实际学习开始日期: | 11/30/2013 |
| 预计主要完成日期: | 06/30/2014 |
| 预计完成日期: | 07/31/2014 |
状况或疾病
干预/治疗
Dietary Supplement: Intervention group
Other: Nutritional counseling
Behavioral: Physical activity counseling
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: Intervention group Patients in the intervention group were given dietary supplement (Improved Atta: 100 g) daily along with nutritional counseling and physical activity counseling for six months. | Dietary Supplement: Intervention group Improved Atta is a multi macro- micronutrient bread mix. Patients were given 100 grams of Improved Atta (in the from of unleavened bread) everyday for consumption for six months. |
| Other: Control group Patients in the control group were given nutritional and physical activity counseling for six months every fortnight. |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | Female |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Female, age 18 years and above. - Diagnosed with cancer. - Weight loss >5% from pre-treatment weight or BMI<20kg/m2. - Hemoglobin level <12 g/dl. - Energy intake < 1500 kcal/d (to be assessed on consultation). Exclusion Criteria: - Incapable to provide written consent. - Patient diagnosed with refractory cachexia. - Life expectancy < 3 months. - Unresponsive to anti-cancer therapy. - Patient is a pregnant woman or a nursing mother. - Suffering from secondary illnesses. - Gastrointestinal tract defects which affect nutrient absorption |
结果
主要结果指标
1. Body weight [6 months]
次要成果指标
1. Mid upper arm circumference (MUAC) [6 months]
2. Body fat percentage (BF%) [6 months]
3. Nutritional status assessment (Indian Migrant study food frequency questionnaire (IMS-FFQ), two day 24 hour dietary recall and patient generated subjective global assessment) [6 months]
4. Physical activity assessment (Indian Migrant Study Physical Activity questionnaire (IMS-PAQ) [6 months]
5. Quality of life (QoL) assessment (EORTC-QLQ- C30 questionnaire) [6 months]
6. Haemoglobin (Haemoglobin levels) [6 months]
7. Serum albumin (Serum albumin levels) [6 months]
