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Molecular Characteristics of the Persistent Intestinal Fistulae After Glue Application

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Jianan Ren

关键词

抽象

For non-healing ulcers, abnormal periods of wound healing processes: inflammation, proliferation and remodelling, are believed to lead to chronic wounds. As a chronic "stalled" wound, investigators hypothesized that these glue-assisted closure (GAC)-failed enterocutaneous fistula (ECF) might have a prolonged inflammatory phase modulated by excessive pro-inflammatory cytokines or proteases. The aim of this study was to analyze the chemicals in ECF wounds in order to determine patients' condition and fitness for GAC.

日期

最后验证: 10/31/2013
首次提交: 11/10/2013
提交的预估入学人数: 11/20/2013
首次发布: 11/24/2013
上次提交的更新: 11/20/2013
最近更新发布: 11/24/2013
实际学习开始日期: 12/31/2011
预计主要完成日期: 02/28/2013
预计完成日期: 02/28/2013

状况或疾病

Enterocutaneous Fistulas

-

资格标准

有资格学习的年龄 18 Years 至 18 Years
有资格学习的性别All
取样方式Non-Probability Sample
接受健康志愿者
标准

Inclusion Criteria:

- above 18 years old;

- single tubular (tract length >2 cm) ECF;

- low output volume (<200 ml/24h);

Exclusion Criteria:

- fistulas of cancer-infiltrated;

- associated abscess;

- foreign bodies;

- distal bowel obstruction;

结果

主要结果指标

1. Fistula closure after glue application [7 days]

No fistula output

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*所有信息均基于已发表的科学研究

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