Monocyte Chemoattractant Protein-1 2518A/G Polymorphism
关键词
抽象
描述
The association between polymorphism of MCP-1 c.2518A/G and DR had been reported in Japan and Korea, but their opinion were inconsistent. However there is no report in China so far. This study was designed to clarify the relationship of polymorphism of MCP-1 c.2518A/G with type 2 diabetes with or without DR. The relationship between MCP-1 c.2518A/G and different stage of DR has also been studied.This article proved that the MCP-1 c.2518G/G genotype is a susceptibility gene for DR in Chinese type 2 diabetic patients, especially the High-risk PDR. There is no association with DME and c.2518G/G.
日期
| 最后验证: | 02/28/2014 |
| 首次提交: | 06/09/2013 |
| 提交的预估入学人数: | 02/27/2014 |
| 首次发布: | 03/03/2014 |
| 上次提交的更新: | 03/02/2014 |
| 最近更新发布: | 03/04/2014 |
| 实际学习开始日期: | 08/31/2011 |
| 预计主要完成日期: | 01/31/2013 |
| 预计完成日期: | 03/31/2013 |
状况或疾病
相
资格标准
| 有资格学习的年龄 | 41 Years 至 41 Years |
| 有资格学习的性别 | All |
| 取样方式 | Non-Probability Sample |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Type 2 diabetic retinopathy - age at diagnosis ≥30 years and a known duration of diabetes of ≥5 years. Exclusion Criteria: - eyeball atrophy - epimacular membrane - age-related macular degeneration (ARMD) - intravitreal injection medicine - vitreous hemorrhage |
结果
主要结果指标
1. Genetic association [1 year]
