Nasopharyngeal Carriage of S. Pneumoniae
关键词
抽象
描述
Since September 2001, 121 pediatricians who are part of a research and teaching network (ACTIV) throughout France participated at this prospective study. From October to June of each subsequent year, children of both sexes suffering from suppurative acute otitis media (AOM) with fever and/or otalgia (in order to increase the probability of pneumococcal AOM), aged 6 to 24 months, were enrolled.
日期
| 最后验证: | 06/30/2020 |
| 首次提交: | 06/18/2020 |
| 提交的预估入学人数: | 06/30/2020 |
| 首次发布: | 07/06/2020 |
| 上次提交的更新: | 07/07/2020 |
| 最近更新发布: | 07/09/2020 |
| 实际学习开始日期: | 09/10/2001 |
| 预计主要完成日期: | 08/31/2023 |
| 预计完成日期: | 08/31/2023 |
状况或疾病
干预/治疗
Other: prospective cohort
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Other: prospective cohort Nasopharyngeal sample for each enrrolled children | Other: prospective cohort nasopharyngeal swabs from children with acute otitis media aged 6 to 24 months. The swabs were analyzed by the French National Reference Centre for Pneumococci. |
资格标准
| 有资格学习的年龄 | 6 Months 至 6 Months |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - both sexes - suffering from suppurative AOM - age: 6 months to 24 months for AOM - age: 6 months to 15 years for healthy children - informed consent from parents or guardians Exclusion Criteria: - Children with antibiotic treatment within 7 days before enrolment, - severe underlying disease, - inclusion in the study during the previous 12 months |
结果
主要结果指标
1. S. Pneumoniae colonisation to detect emerging serotypes [at inclusion]
次要成果指标
1. Detect the emergence of resistance S. pneumoniae [at inclusion]
2. Evaluation of the rhinopharyngeal carriage of other bacteria [at inclusion]
3. Detect the emergence of new serotypes [at inclusion]
