Ocular Finding in Alopecia Areata
关键词
抽象
描述
Alopecia areata is now considered a systemic autoimmune disease that may have other serious comorbidities, such as cardiovascular and ocular. However, the results of studies of ocular findings in AA are controversial.
Several ocular alterations have been previously reported in patients with AA ranging from minor punctate opacities to cataract. However, there are contrasting opinions on the significance of these lenticular changes. In addition, Horner syndrome, pupil ectopia, iris atrophy, fundus changes , bilateral keratoconus, iris changes and retinal changes have been reported in AA.
Dermoscopy is a noninvasive, diagnostic tool which visualizes subtle patterns of skin lesions not normally visible to the unaided eye. Characteristic dermoscopic finding of AA included black dots , tapering hair corresponding to " exclamation mark hairs " , broken hairs , yellow dots , and clustered short vellus hairs ( shorter than 10 mm).
Since ocular affection can be a profound morbidity factor in patients with AA, we will search deeply in this study about this correlation in order to conclude the value of ocular screening in each and every patient with AA.
日期
最后验证: | 04/30/2017 |
首次提交: | 05/14/2017 |
提交的预估入学人数: | 05/14/2017 |
首次发布: | 05/15/2017 |
上次提交的更新: | 05/14/2017 |
最近更新发布: | 05/15/2017 |
实际学习开始日期: | 06/30/2017 |
预计主要完成日期: | 06/30/2019 |
预计完成日期: | 12/31/2019 |
状况或疾病
相
资格标准
有资格学习的性别 | All |
取样方式 | Non-Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - patients of alopecia areata will be recruited from the Dermatology Outpatients' Clinic, Assiut University Hospitals, Assiut, Egypt. Exclusion Criteria: 1. Patients with documented eye disease. 2. Patients with any systemic illness. 3. Patients who received any systemic treatment with possible ocular implications in the last three months. |
结果
主要结果指标
1. the number of patient with occular affection in alopecia areata [2 years]
次要成果指标
1. correlate dermoscopic finding with disease severity and ocular finding [2 years]