Prevalence of Delayed Chemotherapy Associated Nausea
关键词
抽象
描述
Chemotherapies are rated to have a high to minimal emetogenic potential in oncology patients. Their potential to induce delayed nausea is supposed to often be higher than their emetogenic potential. However, data on delayed chemotherapy-related nausea are scarce, which is problematic because nausea (a) has a large impact on patients quality of life and treatment decisions, (b) is often underestimated by health care professionals, (c) is less responsive to commonly used antiemetic medication, and (d) may even be different from rates that have been established in controlled clinical trials.
Therefore, the aim of this study is to assess the prevalence of delayed chemotherappy-induced nausea in adult oncology patients in dayclinics.
日期
| 最后验证: | 03/31/2020 |
| 首次提交: | 03/24/2020 |
| 提交的预估入学人数: | 04/08/2020 |
| 首次发布: | 04/12/2020 |
| 上次提交的更新: | 04/19/2020 |
| 最近更新发布: | 04/21/2020 |
| 实际学习开始日期: | 06/28/2020 |
| 预计主要完成日期: | 12/30/2021 |
| 预计完成日期: | 04/30/2022 |
状况或疾病
相
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 取样方式 | Non-Probability Sample |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - first day of chemotherapy of a new cycle (any cycle) - speak and write German - sign the consent forms Exclusion Criteria: - cognitive or linguistic impairments that would significantly impede consent or participation (as assessed by the nurses in charge) - accompanying radiotherapy; - pre-existing nausea within three days before the start of the first chemotherapy in this cycle; and - prior participation in CINrate (each person participates only once) |
结果
主要结果指标
1. delayed Nausea [Each patient: each days for 5 days after chemotherapy; recruitment: six weeks]
次要成果指标
1. acute nausea [Each patient: at day of chemotherapy at discharge from dayclinic; recruitment: six weeks]
2. acute and delayed vomiting [Each patient: each day for 5 days after chemotherapy; recruitment: six weeks]
3. adherence to antiemetics [Each patient: each day for 5 days after chemotherapy; recruitment: six weeks]
4. antiemetic prescription [Each patient: at day of chemotherapy at discharge from dayclinic; recruitment: six weeks]
5. interference of nausea or vomiting with everyday life [Each patient: measured at day 5 after chemotherapy; recruitment: six weeks]
6. patient-related barriers to antiemetics [Each patient: measured at day 5 after chemotherapy; recruitment: six weeks]
