Pulsed Radiofrequency in Chronic Headaches
关键词
抽象
描述
Patients participating suffered from primary headaches (migraine, cluster, and tension headache) and occipital neuralgia were enrolled in the study. They have all received in the past the standard systemic pharmacotherapy prophylaxis for headache management (with topiramate or amitriptylline) as well as tryptanes for rescue treatment, and were scheduled for a diagnostic nerve block of the occipital nerves in cases of intractable pain. Inclusion criteria included: not adequate response to systemic pharmacotherapy, pain over crises of >4/10, occipital tenderness bilaterally or unilaterally, and days with headache of more than 10/month. Exclusion criteria were age<18 years old, pregnancy or lactation, presence of cardiac pacemaker, previous therapy with PRF, severe psychiatric disorder and patient refusal. In cases of a positive response to the diagnostic nerve block with local anesthetic, with >50% pain relief they were scheduled for pulsed radiofrequency of GON and LON bilaterally.
Primary outcome measure was the days with headache per month, before and after treatment. In addition, pain during headache crisis (with Visual Analogue Scale, VAS, 0-10), the analgesic consumption (number per month) and the quality of life (measured with EQ6D) were studied. All measurements were performed before treatment, as well as after 1, 3, 6, and 12 months. All patients completed the Brief Pain Inventory questionnaire in Greek language and signed an informed consent prior treatment. All measurements were accomplished by an independed (blinded) researcher of the pain unit. All complications and side effects were also recorded.
日期
最后验证: | 03/31/2020 |
首次提交: | 04/05/2020 |
提交的预估入学人数: | 04/05/2020 |
首次发布: | 04/08/2020 |
上次提交的更新: | 04/05/2020 |
最近更新发布: | 04/08/2020 |
实际学习开始日期: | 02/28/2019 |
预计主要完成日期: | 11/30/2020 |
预计完成日期: | 11/30/2021 |
状况或疾病
干预/治疗
Procedure: Pulsed radiofrequency of the occipital nerves
相
资格标准
有资格学习的年龄 | 18 Years 至 18 Years |
有资格学习的性别 | All |
取样方式 | Non-Probability Sample |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - not adequate response to systemic pharmacotherapy - pain over crises of >4/10 - occipital tenderness bilaterally or unilaterally, - days with headache of more than 10/month. Exclusion Criteria: - age<18 years old, - pregnancy or lactation - presence of cardiac pacemaker - previous therapy with PRF - severe psychiatric disorder - severe coagulopathy - patient refusal |
结果
主要结果指标
1. Days with headache [12 months]
次要成果指标
1. pain during crisis [12 months]
2. analgesics consumption [12 months]
3. quality of life [12 months]