Setria Performance Blend Supplementation
关键词
抽象
描述
This study is a randomized, double-blind, placebo-controlled crossover trial in healthy men. Subjects will take either a placebo or setria performance blend (L-citrulline + glutathione) for 8 days. At the day 8, subjects run on the treadmill to measure the time to exhaustion at 90%, 100%, and 110% of peak velocity. Arterial blood flow and blood vessel diameter (via ultrasound), blood analytes (plasma nitrate/nitrite, L-arginine, L-citrulline), subjective feelings of fatigue from a visual analog scale (VAS) and ratings of perceived exertion will be assessed.
日期
| 最后验证: | 03/31/2020 |
| 首次提交: | 09/11/2019 |
| 提交的预估入学人数: | 09/11/2019 |
| 首次发布: | 09/15/2019 |
| 上次提交的更新: | 04/28/2020 |
| 最近更新发布: | 04/29/2020 |
| 实际学习开始日期: | 11/29/2019 |
| 预计主要完成日期: | 09/30/2021 |
| 预计完成日期: | 09/30/2021 |
状况或疾病
干预/治疗
Dietary Supplement: Setria performance blend
Dietary Supplement: Placebo
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Active Comparator: Setria performance blend l-citrulline + glutathione | Dietary Supplement: Setria performance blend Oral capsules |
| Placebo Comparator: Placebo | Dietary Supplement: Placebo Oral capsules |
资格标准
| 有资格学习的年龄 | 20 Years 至 20 Years |
| 有资格学习的性别 | Male |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Participant is an adult male between the ages of 20-30 years - Participant is aerobically fit, as defined by a VO2max between 42-70 ml*kg/min (determined by the screening test) - Participant is not obese (18.5 ≦ BMI < 30 kg/m²) - Participant has provided written and dated informed consent to participate in the study - Participant is willing and able to comply with the protocol - Participant is apparently healthy and free from disease, as determined by a health history questionnaire - Participant agrees to refrain from strenuous exercise and alcohol consumption within 24 hours of laboratory visits, and to refrain from caffeine consumption within twelve hours of visits - Participant agrees to refrain from using antibacterial mouthwash, chewing gum, and brushing their teeth on the morning of laboratory visits Exclusion Criteria: - Participant has consistently used prescription drugs or ergogenic dietary supplements that may influence study outcomes within eight weeks prior to enrollment, or begins to do so during the study. Potential drugs and supplements include but are not limited to whey protein, creatine, beta-alanine, antihypertensive medications, or anabolic steroids - Participant has gained or lost ≥10 lbs in the previous 2 months - Participant is enrolled in a separate clinical trial involving diet, exercise, physical activity, or the potential ingestion of an active drug or dietary supplement in the previous 2 months and during this study - Participant has participated in a clinical trial within the previous 2 months that includes modifications to their physical and/or diet that may influence study outcomes and during this study - Participant has a known allergy or sensitivity to the placebo or active ingredients - Participant consumes more than 3 alcoholic drinks per day - Participant has used tobacco more than three days per week (on average) in the previous eight weeks - Participant has used recreational drugs within the past month, or refuses to abstain from recreational drug use for the entirety of the study |
结果
主要结果指标
1. Change in Time to exhaustion (sec) [8 days]
2. Change in Blood Flow (ml/min-1) [8 days]
3. Change in Vessel Diameter (mm) [8 days]
