Soda and Milk Study
关键词
抽象
日期
最后验证: | 09/30/2017 |
首次提交: | 03/19/2014 |
提交的预估入学人数: | 03/20/2014 |
首次发布: | 03/23/2014 |
上次提交的更新: | 10/30/2017 |
最近更新发布: | 11/05/2017 |
实际学习开始日期: | 03/31/2014 |
预计主要完成日期: | 08/31/2016 |
预计完成日期: | 04/30/2017 |
状况或疾病
干预/治疗
Dietary Supplement: Reduced Fat Milk
Dietary Supplement: Sugar Sweetened Soda
相
手臂组
臂 | 干预/治疗 |
---|---|
Experimental: Reduced Fat Milk 20 oz. reduced fat (2%) milk per day | Dietary Supplement: Reduced Fat Milk Subjects will be provided with and instructed to consume the equivalent of 20oz. reduced fat milk per day for 3 weeks |
Experimental: Sugar Sweetened Soda 24oz. soda per day | Dietary Supplement: Sugar Sweetened Soda Subjects will be provided with and instructed to consume 2 cans (24oz) of sugar sweetened soda per day for 3 weeks |
资格标准
有资格学习的年龄 | 13 Years 至 13 Years |
有资格学习的性别 | Male |
接受健康志愿者 | 是 |
标准 | Inclusion Criteria: - Males, age 13-18 - Tanner stage ≥ 2 - Self reported sugar sweetened beverage intake 24oz to 60oz per day - Self reported milk intake ≤16 oz. per day - BMI 85-99 percentile for age - Tolerant to milk Exclusion Criteria: - History or diagnosis of hypertension or taking blood pressure lowering medication - History or diagnosis of diabetes, HbA1c ≥ 6.5% or fasting glucose ≥ 126 mg/dl - Fasting triglyceride > 300 mg/dl - On lipid lowering or diabetes medication |
结果
主要结果指标
1. LDL peak particle diameter [3 weeks]
次要成果指标
1. Plasma triglycerides [3 weeks]
2. LDL-cholesterol [3 weeks]
3. HDL-cholesterol [3 weeks]
4. Blood pressure [3 weeks]
5. LDL subclass concentrations [3 weeks]
6. Apolipoprotein B [3 weeks]
7. Apolipoprotein AI [3 weeks]
8. Apolipoprotein CIII [3 weeks]