Unilateral Wrist Extension Training After Stroke
关键词
抽象
描述
Stroke produces muscle weakness seen on both more (paretic, MA) and less affected (non-paretic, LA) sides. "Cross-education" is training one side of the body increases strength or motor skill in the same muscles on the untrained side. This can be applied to enhance muscle strength in the MA side and we found that 6 weeks of dorsiflexion resistance training with the LA leg improved strength bilaterally in chronic stroke. To explore if cross-education occurs also in the upper limb after stroke, participants will complete a 5-week unilateral wrist extension training.
Twenty four participants will be recruited, 12 from Rehabilitation Neuroscience laboratory at University of Victoria, 12 from Brain Behaviour Laboratory at University of British Columbia. Before and after training, maximal voluntary contraction wrist extension force was measured with a 6-axis load cell using Cartesian coordinates (Fz = extension). Electromyography of extensor and flexor carpi radialis, biceps and triceps brachii were recorded. Fugl-Meyer and partial Wolf Motor Function Test were performed by the same physical therapist at each location. Reciprocal inhibition from wrist flexors to extensors, cutaneous reflexes evoked by median and superficial radial nerve stimulation were assessed in those at UVIC. Cortical silent period, short-interval intracortical inhibition, intracortical facilitation and transcallosal inhibition from transcranial magnetic stimulation were measured in participants at UBC.
日期
| 最后验证: | 07/31/2017 |
| 首次提交: | 08/23/2017 |
| 提交的预估入学人数: | 08/28/2017 |
| 首次发布: | 08/30/2017 |
| 上次提交的更新: | 08/28/2017 |
| 最近更新发布: | 08/30/2017 |
| 实际学习开始日期: | 02/28/2015 |
| 预计主要完成日期: | 06/30/2017 |
| 预计完成日期: | 06/30/2017 |
状况或疾病
干预/治疗
Device: Wrist extension training
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Experimental: Wrist extension training | Device: Wrist extension training Participants will join a five-week training protocol with 3 sessions per week. During each session, 5 sets 5 maximal wrist extension training will be performed on participants less affected side. |
资格标准
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - Over 6 months post-stroke; - One side of arm shows muscle weakness - Pass the screening test of Physical Activity Readiness Questionnaire - Pass the screening test for dementia - Free from dementia (score < 24 on the Montreal Cognitive Assessment) and any other contradiction for TMS test Exclusion Criteria: - Had medication affecting muscle tone within the past 3 months - Wear a pacemaker |
结果
主要结果指标
1. Changes in wrist extension force [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test; Week 13: follow-up test]
次要成果指标
1. Changes in the modulation of spinal-mediated muscle reflexes [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test;]
2. Neural adaptation in the corticospinal pathway [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test;]
3. Upper limb impairment assessments [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test;]
4. Upper limb function assessments [Week1-3: baselines were measured once per week for three times; Week 4-8: training (no measurement was taken); Week 9: post-test; Week 13: follow-up test]
5. Ten-meter walking test [Week1-3: baselines were measured once per week for three times; Week 4-8: training (no measurement was taken); Week 9: post-test;]
6. Six-minute walking test [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test;]
7. Timed up and go [Week1-3: baselines were measured once per week for three times; Week 4-8: training(no measurement was taken); Week 9: post-test;]
