Yoga Breathing for Fatigue in Patients Undergoing Chemotherapy
关键词
抽象
描述
Fatigue is the most common complaint among cancer patients. This pilot study will evaluate the effects of pranayama (ancient yoga breathing techniques) on fatigue and quality of life among 30 patients undergoing chemotherapy, on an every 2, 3, or 4 week schedule, with a fatigue score of at least 4 on a scale of 0 (none) to 10 (most). Patients will be randomized to either pranayama or wait-list control. The pranayama group will learn and practice 3 breathing techniques on a daily basis. The study period will occur during 2 consecutive cycles of chemotherapy (cycle A and Cycle B), and the wait-list control patients will crossover to the treatment arm at the beginning of his/her Cycle B. Fatigue will be measured using the revised Piper Fatigue Scale along with quality of life measures. These study measures will be conducted at baseline, at the end of cycle A, and at the end of cycle B. We hypothesize that pranayama will improve clinical symptoms of fatigue and quality of life among patients undergoing chemotherapy.
日期
| 最后验证: | 07/31/2011 |
| 首次提交: | 09/17/2009 |
| 提交的预估入学人数: | 09/21/2009 |
| 首次发布: | 09/22/2009 |
| 上次提交的更新: | 08/22/2011 |
| 最近更新发布: | 08/24/2011 |
| 实际学习开始日期: | 09/30/2008 |
| 预计主要完成日期: | 11/30/2009 |
| 预计完成日期: | 11/30/2009 |
状况或疾病
干预/治疗
Behavioral: Pranayama (Yoga Breathing) Techniques
相
手臂组
| 臂 | 干预/治疗 |
|---|---|
| Active Comparator: Group B Study participants in this arm attend yoga breathing classes once per week over the span of one chemotherapy cycle. | |
| Experimental: Group A Participants in this study arm attend weekly yoga breathing classes during two consecutive cycles of chemotherapy |
资格标准
| 有资格学习的年龄 | 18 Years 至 18 Years |
| 有资格学习的性别 | All |
| 接受健康志愿者 | 是 |
| 标准 | Inclusion Criteria: - A diagnosis of cancer that requires at least 2 further cycles of chemotherapy on an every 14, 21, or 28 day schedule - A score of at least 4/10 on a 0-10 (0-none, 10-most) visual analog scale for fatigue at the time of enrollment - Able to read, write and understand English - Karnofsky Performance Status greater than 60 - Ability to give informed consent Exclusion Criteria: - Severe COPD - Receiving chronic oxygen therapy - Congestive heart failure: NYHA class 3 or greater - Transfusion dependent anemia - Uncontrolled thyroid disease - Advance kidney disease requiring dialysis - Advance liver disease - More than three previous chemotherapy regimens - Current, ongoing yoga breathing practice |
结果
主要结果指标
1. Feasibility [Baseline and second cycle of chemotherapy]
次要成果指标
1. Cancer associated symptoms and quality of life [baseline and final cycle of chemotherapy]
