Bioscience, Biotechnology and Biochemistry 1995-Aug
1'-Acetoxychavicol acetate as an inhibitor of phagocytosis of macrophages.
只有注册用户可以翻译文章
登陆注册
链接已保存到剪贴板
关键词
抽象
We screened extracts of edible plants for inhibitors of phagocytosis by peritoneal exudate macrophages. 1'-Acetoxychavicol acetate was isolated from the ethyl acetate extract of Languas galanga, and this compound strongly inhibited phagocytosis at an IC50 value of 1.2 microM with negligible effects on pinocytosis and cell viability. Target(s) of 1'-acetoxychavicol acetate was suggested to be downstream of the signal transduction pathway that is mediated by protein kinase C.