American journal of optometry and physiological optics 1980-Jun
Acute systemic toxicological tests of soft contact lens extractives.
只有注册用户可以翻译文章
登陆注册
链接已保存到剪贴板
关键词
抽象
The toxic potential of three major components of soft contact lenses was assessed in white mice. Accepted procedures for toxicological studies were used to evaluate the effects of 2-hydroxyethyl methacrylate, ethylene glycol, and methacrylic acid. No observable signs of gross toxicity were detected in any of the mice injected with the original doses. Larger doses of methacrylic acid produced ataxia, irregular breathing, convulsions, and death. From the concentrations of these chemicals normally occurring in contact lenses, no systemic toxic effects would be expected.